Table 2.
Predicted conformational B-cell epitopes from 3D structure of designed chimeric multiepitope vaccines using DiscoTope 2.0 server.
Position | Residues | Contact No. | DiscoTope score (−1.0 threshold) | DiscoTope score (−2.5 threshold) | DiscoTope score (−3.7 threshold) |
---|---|---|---|---|---|
45F2 model | |||||
P | 4 | −2.633 | |||
15 | Q | 3 | −3.581 | ||
45 | E | 6 | −3.527 | ||
49 | K | 11 | −2.743 | ||
53 | S | 7 | −2.246 | −2.246 | |
56 | S | 7 | −0.053 | −0.053 | −0.053 |
57 | E | 0 | 0.238 | 0.238 | 0.238 |
58 | E | 0 | −0.324 | −0.324 | −0.324 |
59 | N | 16 | −2.917 | ||
60 | Q | 1 | −1.810 | −1.810 | |
62 | P | 6 | −2.347 | −2.347 | |
76 | |||||
42E2 model | |||||
14 | K | 0 | −3.101 | ||
18 | T | 2 | −3.663 | ||
22 | E | 8 | −3.441 | ||
25 | D | 9 | −3.374 | ||
26 | T | 0 | −0.847 | −0.847 | −0.847 |
28 | K | 7 | −2.914 | ||
30 | P | 5 | −2.396 | −2.396 | |
31 | E | 17 | −2.830 | ||
124 | D | 0 | −2.791 | ||
125 | G | 3 | −2.887 | ||
129 | S | 0 | −3.612 |