Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 17;10:608. doi: 10.1038/s41598-020-57484-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Biphasic regulation of pRSK by the Standard protocol (five 5-min pulses of 5-HT, 50 μM). (A) Representative confocal images of pRSK immunofluorescence in SNs at different times after the end of 5-HT. Scale bar, 20 μm. (B) Summary data. The percent change was calculated as the change of pRSK level after 5-HT compared to the control level. pRSK was elevated at 1 h after treatment, followed by a decrease at 2 h. A second wave of increase was evident at 5 h, and pRSK levels returned to basal levels at 24 h. Statistical analysis (Wilcoxon signed rank test with Bonferroni correction) revealed significant differences between Veh and 5-HT treatment groups at 1 h and 5 h.