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. 2020 Jan 17;10:608. doi: 10.1038/s41598-020-57484-y

Figure 5.

Figure 5

Knock down of the expression of RSK by siRNA injection reduced LTF. (A) Representative EPSPs recorded immediately before (pre-test) and 24 h after (post-test) treatment with 5-HT. Dashed lines represent the amplitude of the pre-test EPSP. (B) Summary data. RSK-siRNA significantly reduced 5-HT-induced LTF [(Con-siRNA, 5-HT), n= 6; (RSK-siRNA, Veh), n= 6; (RSK-siRNA, 5-HT), n = 6].