Table 1.
Lab monitorization of the patient (days indicate hospitalization and withdrawal periods)
| ALT (U/L) | AST (U/L) | ALP (U/L) | GGT (U/L) | D. Bil (mg/dL) | T. Bil (mg/dL) | Albumin (g/dL) | INR | |
|---|---|---|---|---|---|---|---|---|
| 1-year ago-first hospitalization with “probable” DILI | 1256 | 989 | 156 | 256 | 5.36 | 7.02 | - | - |
| 6 months ago-control | 30 | 25 | 72 | 49 | 0.28 | 0.97 | 3.92 | 1.10 |
| Day 1 | 4133 | 1630 | 146 | 399 | 9.06 | 11.86 | 4.68 | 1.12 |
| Day 7 | 1524 | 1233 | 104 | 116 | 7.72 | 11.39 | 3.74 | 1.18 |
| Day 14 | 947 | 395 | 85 | 91 | 1.83 | 2.93 | 3.89 | 1.07 |
| Day 21 | 432 | 128 | 84 | 81 | 1.06 | 1.82 | 3.96 | 1.09 |
| Day 28 | 122 | 56 | 76 | 56 | 0.34 | 1.20 | 4.12 | 1.08 |
| Day 180 (outpatient) | 28 | 20 | 68 | 51 | 0.25 | 0.93 | - | -- |
DILI, drug induced liver injury; ALT, alanine aminotransferase; AST, aspartat aminotransferase; ALP, alkaline phosphatase; GGT, gamma glutamyl transferase; D. Bil, direct bilirubine; T. Bil, total bilirubine; INR, international normalized ratio; U/L, units per litre; mg/dL, milligrams per decilitre; g/dL, grams per decilitre