Table 2.
Univariate and multivariate analyses of IRGS, clinical and pathologic factors of patients in training cohort
| Characteristic | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| IRGS | 3.69 (2.73–4.98) | < 0.001 | 3.62 (2.58–5.09) | < 0.001 |
| Age | 1.02 (1.00–1.03) | 0.01 | 1.02 (1.00–1.03) | < 0.01 |
| Gender | 0.71 (0.53-0.96) | 0.03 | 0.90 (0.65–1.26) | 0.55 |
| TNM stage | 1.38 (1.14–1.65) | < 0.001 | 1.24 (1.02–1.50) | 0.03 |
| Pathological grading | 1.14 (0.93–1.39) | > 0.05 | NA | NA |
| Smoking | NA | NA | NA | NA |
| Alcohol abuse | 1.01 (0.74–1.37) | > 0.05 | NA | NA |
| HPV | 1.20 (0.88–1.63) | > 0.05 | NA | NA |