Fig. 5.

The network of the most important candidate modules among three diseases, in which the nodes represent DEGs. Hexagons represent the top 10 hubs of the module. Reported DEGs in DisGeNET are indicated in red. Novel DEGs are indicated in blue. The size of nodes reveals the degree level so that the higher degree is depicted by the larger size. a The network of the Skyblue module in asthma. In this module, 10 hub DEGs and 8 adjacency DEGs are involved. b The network of the brown module in COPD. In this module, 10 hub DEGs and 104 adjacency DEGs are implicated. c The network of the black module in IPF. In this module, 10 hub DEGs and 37 adjacency DEGs are involved. d The network of the turquoise module in the asthma-COPD in which red circles represent shared DEGs in asthma and COPD and, turquoise circles represent just DEGs in asthma and, green circles represent just DEGs in COPD. In this module, 10 hub DEGs and 57 adjacency DEGs are implicated. e The network of the turquoise module in the asthma-IPF in which red circles represent shared DEGs in asthma and IPF and, turquoise circles represent just DEGs in asthma and, green circles represent just DEGs in IPF. In this module, 10 hub DEGs and 17 adjacency DEGs are involved. f The network of the turquoise module in COPD-IPF in which red circles represent shared DEGs in COPD and IPF and, turquoise circles represent just DEGs in COPD and, green circles represent just DEGs in IPF. In this module, 10 hub DEGs and 61 adjacency DEGs are involved