Table 2.
Treatment details and postoperative outcomes in the three groups
| Characteristics | Sequential resection (n=49) | Delayed resection (n=98) | Simultaneous resection (n=86) | p† | p‡ | p§ |
|---|---|---|---|---|---|---|
|
Initial chemotherapy Yes/no |
41/8 | 26/72 | 66/20 | <0.001 | 0.340 | <0.001 |
|
Biologic agents (Yes/no) |
17/32 | 10/88 | 30/56 | <0.001 | 0.982 | <0.001 |
|
Adjuvant chemotherapy Yes/no |
39/10 | 68/30 | 64/22 | 0.190 | 0.497 | 0.450 |
|
Hepatectomy Major/minor |
21/28 | 31/67 | 29/57 | 0.180 | 0.290 | 0.763 |
|
Combined with RFA Yes/no |
7/42 | 11/87 | 5/81 | 0.594 | 0.177 | 0.194 |
|
Hilar vascular clamp Yes/no |
46/3 | 82/16 | 66/20 | 0.082 | 0.011 | 0.237 |
| Blood loss, ml (range) | 200 (80-1400) | 200 (70-1000) | 200 (100-3200) | 0.709 | 0.132 | 0.024 |
| Differentiation of metastases | 0.762 | 0.594 | 0.127 | |||
| Well/Moderate/Poor | 3/39/7 | 7/81/10 | 6/62/18 | |||
|
Margin status R0/R1 |
39/10 | 81/17 | 74/12 | 0.651 | 0.329 | 0.528 |
| Any morbidity | 0.514 | 0.382 | 0.016 | |||
| Grade 0 | 29 | 67 | 44 | |||
| Grade 1-2 | 12 | 20 | 19 | |||
| Grade 3-4 | 8 | 11 | 23 | |||
| Overall morbidity, n (%) | 20 (40.8) | 31 (31.6) | 42 (48.8) | 0.270 | 0.369 | 0.017 |
| Cumulative major complications, n (%) | 8 (16.3) | 11 (11.2) | 23 (26.7) | 0.385 | 0.166 | 0.007 |
Values are presented as medians and ranges.
†Sequential resection group versus delayed resection group
‡Sequential resection group versus simultaneous resection group
§Delayed resection group versus simultaneous resection group