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. 2019 Dec 31;117(2):1042–1048. doi: 10.1073/pnas.1914181117

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Fig. 2. — Overall structure of the human LDB1/SSBP2 complex. (A) Structure of 1 LDB1 in complex with 1 SSBP2 dimer. One SSBP2 dimer binds to 1 LDB1 LCCD domain. LDB1 NTF2-like subdomain, H4-H5 subdomain, and LCCD are colored in orange, magenta, and red, respectively. SSBP2 dimers are colored in green and cyan. (B) The “LDB1-only” structure in the complex. There is an H4-H5 subdomain between the main dimerization domain (NTF2-like subdomain) and LCCD. (C) Two orthogonal views of the LDB1/SSBP2 complex structure, which contains a symmetric LDB1 dimer, with each LDB1 monomer interacting with 1 SSBP dimer.