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. 2019 Dec 27;117(2):836–847. doi: 10.1073/pnas.1912500117

Fig. 1.

Fig. 1.

Multiple modes of pattern formation by single-cell transcriptional activity. (A–D) Cytoplasmic mRNA patterns (A) could arise from transcription factors exerting control over the mean transcription rate (B), the transcriptional time window dictating when a nucleus is transcriptionally active or quiescent (C), or the fraction of active nuclei (D) or some combination thereof.