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. 2020 Jan 14;12:277–287. doi: 10.2147/CMAR.S220351

Figure 2.

Figure 2

Down-regulation of CASC9 inhibited cell proliferation, migration and invasion of TSCC cells. (A) CAL27 and Tca8113 cells were transfected with siCASC9-1 or siCASC9-2, or siCtrl plasmids, the mRNA expression of CASC9 was examined by RT-qPCR analysis. (B) Cell proliferation of CAL27 and Tca8113 cells transfected with siCASC9 or siCtrl was determined by CCK8 assay. (C and D) Cell migration and invasion of CAL27 and Tca8113 cells transfected with siCASC9 or siCtrl were detected by transwell assay. (E) Tumor growth curves were established by measuring tumor volume every 7 for 42 days after injection. (F) Tumor weights isolated from nude mice in each treatment group were determined on day 42 after injection. Data is from three independent experiments and expressed as mean ± SD. **P<0.01, ***P<0.001 compared with siCtrl.