Table 3.
Simple and Multiple Linear Regression Analyses of the Variables Correlated with Uremic Pruritus Intensity in the Nighttime
| Simple Linear Regression Analysis | Multiple Linear Regression Analysis | |||
|---|---|---|---|---|
| Standard Coefficient | P-value | Standard Coefficient | P-value | |
| Age (years) | 0.218 | 0.15 | ||
| Male sex (yes vs. no) | 0.191 | 0.20 | ||
| Body mass index (kg/m2) | 0.035 | 0.82 | ||
| Peritoneal dialysis vintage (months) | 0.415 | 0.004 | 0.415 | 0.004 |
| CAPD (yes vs. no) | 0.210 | 0.16 | ||
| APD (yes vs. no) | −0.023 | 0.88 | ||
| CAPD and APD (yes vs. no) | −0.187 | 0.21 | ||
| Icodextrin solution (yes vs. no) | −0.190 | 0.21 | ||
| Lactate-buffered solution (yes vs. no) | 0.079 | 0.60 | ||
| Bicarbonate-buffered solution (yes vs. no) | 0.019 | 0.90 | ||
| Weekly total Kt/V | −0.017 | 0.91 | ||
| Weekly renal Kt/V | −0.092 | 0.54 | ||
| Weekly peritoneal Kt/V | −0.054 | 0.72 | ||
| Combined therapy with peritoneal dialysis and hemodialysis (yes vs. no) | 0.207 | 0.17 | ||
| Diabetes mellitus (yes vs. no) | 0.262 | 0.08 | ||
| Diabetic neuropathy (yes vs. no) | 0.069 | 0.65 | ||
| Diabetic angiopathy (yes vs. no) | 0.217 | 0.15 | ||
| Liver disease (yes vs. no) | 0.047 | 0.76 | ||
| Corticosteroid (yes vs. no) | −0.161 | 0.29 | ||
| Antihistamine (yes vs. no) | 0.137 | 0.36 | ||
| Nalfurafine (yes vs. no) | 0.241 | 0.11 | ||
| Topical medicine (yes vs. no) | 0.345 | 0.019 | 0.345 | 0.019 |
| Calcium-containing phosphate binders (yes vs. no) | 0.261 | 0.08 | ||
| Calcium-free phosphate binders (yes vs. no) | −0.073 | 0.63 | ||
| Vitamin D analog (yes vs. no) | 0.102 | 0.50 | ||
| Cinacalcet (yes vs. no) | 0.188 | 0.21 | ||
| Polaprezinc (yes vs. no) | −0.204 | 0.17 | ||
| Erythropoiesis-stimulating agent (yes vs. no) | −0.034 | 0.82 | ||
| Hemoglobin A1c (%) | 0.310 | 0.07 | ||
| Total protein (g/dL) | −0.189 | 0.21 | ||
| Serum albumin (g/dL) | −0.250 | 0.09 | ||
| Blood urea nitrogen (mg/dL) | −0.106 | 0.48 | ||
| Creatinine (mg/dL) | 0.083 | 0.59 | ||
| Uric acid (mg/dL) | 0.010 | 0.95 | ||
| Sodium (mmol/L) | 0.014 | 0.92 | ||
| Potassium (mmol/L) | 0.045 | 0.77 | ||
| Chloride (mmol/L) | 0.162 | 0.28 | ||
| Calcium (mg/dL) | −0.138 | 0.36 | ||
| Phosphate (mg/dL) | 0.099 | 0.51 | ||
| Magnesium (mg/dL) | 0.155 | 0.30 | ||
| Blood sugar (mg/dL) | 0.269 | 0.07 | ||
| Hemoglobin (g/dL) | −0.123 | 0.42 | ||
| Bicarbonate (mmol/L) | −0.132 | 0.39 | ||
| Ferritin (ng/mL) | −0.181 | 0.23 | ||
| β2 microglobulin (mg/L) | 0.151 | 0.32 | ||
| Intact-parathyroid hormone (pg/mL) | −0.091 | 0.55 | ||
Abbreviations: APD, automated peritoneal dialysis; CAPD, continuous ambulatory peritoneal dialysis.