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. 2019 Dec 11;8(12):634. doi: 10.3390/antiox8120634

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Relative mRNA expression levels of selenoprotein, cell-cycle-, and apoptosis-related genes in ovaries of aging mice fed different concentrations of inorganic and organic selenium (Se). Se-D: Se-deficient (sodium selenite 0.08 mg/kg); ISe-A: inorganic Se-adequate (sodium selenite 0.15 mg/kg); ISe-S: inorganic Se-supplemented (sodium selenite 0.33 mg/kg); OSe-A: organic Se-adequate (Se-yeast 0.15 mg/kg); OSe-S: organic Se-supplemented (Se-yeast 0.33 mg/kg) groups. Data are expressed as mean ± SEMs. Values with different lowercase letters (a, b, and c) indicate a significant difference (p < 0.05) between groups within the same variate (gene). Gpx1: glutathione peroxidase 1; Gpx3: glutathione peroxidase 3; Gpx4: glutathione peroxidase 4; Selenof: selenoprotein F; Bcl-2: B-cell leukemia/lymphoma 2; p21 (also called Cdkn1a): cyclin-dependent kinase inhibitor 1A.