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. 2019 Nov 16;8(4):240. doi: 10.3390/pathogens8040240

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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VEEV disease in macaques. Shown is the model of disease for (a) VEEV-exposed macaques over days post-infection (x-axis); all macaques developed febrile encephalitic disease. Deep blue denotes pre-infection baseline period, vertical magenta line denotes time of infection, powder blue defines post-infection period before the onset of fever, red signifies the febrile post-infection period, and yellow signifies recovery period after febrile illness subsides. Actual and forecasted temperature profiles for female macaques: (b) M164-16, (c) M165-16, and male macaques: (d) M170-16 and (e) M171-16. Red: actual temperature (°C); Blue: forecasted temperature (°C) from ARIMA modeling, Black: residual values (°C) (deviations from forecasted baseline). Gray Lines: upper/lower bounds for residuals. Magenta: aerosol challenge.

VEEV disease in macaques. Shown is the model of disease for (a) VEEV-exposed macaques over days post-infection (x-axis); all macaques developed febrile encephalitic disease. Deep blue denotes pre-infection baseline period, vertical magenta line denotes time of infection, powder blue defines post-infection period before the onset of fever, red signifies the febrile post-infection period, and yellow signifies recovery period after febrile illness subsides. Actual and forecasted temperature profiles for female macaques: (b) M164-16, (c) M165-16, and male macaques: (d) M170-16 and (e) M171-16. Red: actual temperature (°C); Blue: forecasted temperature (°C) from ARIMA modeling, Black: residual values (°C) (deviations from forecasted baseline). Gray Lines: upper/lower bounds for residuals. Magenta: aerosol challenge.