Table 3.
Repeated measures ANOVA statistics for QT-interval.
Virus | Macaque | Sex | Dose * | TTD δ | F-Statistic | p-Value |
---|---|---|---|---|---|---|
EEEV | M161-16 | M | 8.2 | 6 | 6.472 | 0.016 * |
M163-16 | M | 7.5 | 6 | 24.95 | 0.00005 * | |
M160-16 | M | 7.0 | S | 3.884 | 0.055 | |
M162-16 | M | 5.7 | S | 2.962 | 0.335 | |
VEEV | M164-16 | F | 7.1 | S | 36.30 | <0.00001 * |
M165-16 | F | 6.9 | S | 62.56 | <0.00001 * | |
M170-16 | M | 6.3 | S | 25.46 | <0.00001 * | |
M171-16 | M | 6.0 | S | 82.35 | <0.00001 * |
Statistics and p-values for QT-interval for EEEV and VEEV-infected macaque cohorts. £ Doses in log10 pfu. δ TTD = time to death. “S” denotes survivor. * p-value lower than significance level α = 0.05.