Scheme 1.
Overview of the preparation of PTX-TSL-siCOX-2(9R/DG-GNS). DPPC: 1,2-dipalmitoyl-sn-glycero-3-phosphocholine; MSPC: 1-stearoyl-2-hydroxy-sn-glycero-3-phosphocholine; DSPE: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine; PTX: Paclitaxel; TSL: temperature sensitive liposomes GNS: gold nanostars; DG: 2-deoxyglucose; 9R: 9-poly-D-arginine; PEG: polyethylene glycol; Cys: cysteine.