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. 2019 Dec 12;11(12):678. doi: 10.3390/pharmaceutics11120678

Table 1.

Physical properties of the solvent cast (SC) film, the electrospun nanofiber (NF) mat, the patterned 3D printed (3D) mat and the bi-layered carriers.

Sample Treatment Thickness a (mm) Puncture Test a Swelling Degree b (%) After 24 h Degradation Degree b (%) After 7 h
Burst Strength (N) Distance at Break (mm)
Solvent Cast (SC) Film
non-crosslinked 0.04 ± 0.01 40.2 ± 14.9 5.0 ± 2.1 NA NA
crosslinked 0.03 ± 0.02 37.4 ± 30.2 3.1 ± 0.9 69 ± 19 1.2 ± 1.2
Electrospun Nanofiber (NF) Mat
non-crosslinked NA NA NA NA NA
crosslinked NA NA NA 401 ± 52 4.9 ± 5.9 c
Patterned 3D Printed (3D) Mat
non-crosslinked 0.04 ± 0.01 5.3 ± 1.1 2.9 ± 0.7 NA NA
crosslinked 0.05 ± 0.01 5.3 ± 1.3 2.6 ± 0.4 75 ± 39 6.7 ± 0.7
Bi-Layered Solvent Cast/Nanofiber (SC/NF) Carrier
non-crosslinked 0.05 ± 0.01 36.8 ± 5.7 6.4 ± 0.8 NA NA
crosslinked 0.09 ± 0.02 45.5 ± 12.4 3.4 ± 0.8 338 ± 35 0.2 ± 0.3
Bi-Layered Solvent Cast /3D Printed (SC/3D) Carrier
non-crosslinked 0.08 ± 0.03 38.4 ± 31.2 4.3 ± 1.8 NA NA
crosslinked 0.11 ± 0.04 31.3 ± 10.9 2.4 ± 0.4 133 ± 20 2.8 ± 0.6

a mean ± standard deviation, n = 10; b mean ± standard deviation, n = 3; c after 24 h; NA—not applicable.