Table 2.
The main characteristics of studies investigating the prognostic value of P21 and overall survival.
| Study | HR | LL | UL | Survival | Statistical method |
|---|---|---|---|---|---|
| Sarbia M 1998 | 0.556 | 0.347 | 0.885 | OS | Multivariable |
| Kuwahara M 1999 | 3.409 | 1.388 | 8.373 | OS | Multivariable |
| Natsugoe S 1999 | 1.920 | 1.065 | 3.460 | OS | Survival curve |
| Shimada Y 1999 | 2.398 | 1.477 | 3.906 | OS | Multivariable |
| Lam KY 1999 | 0.627 | 0.411 | 0.956 | OS | Survival curve |
| Nita ME 1999 | 1.713 | 1.022 | 2.871 | OS | Multivariable |
| GUNER D 2003 | 0.435 | 0.200 | 0.943 | OS | Multivariable |
| Nakamura T 2004 | 1.530 | 1.040 | 2.330 | OS | Multivariable |
| Goan YG 2005 | 0.549 | 0.308 | 0.980 | OS | Multivariable |
| Lin CD 2010 | 2.322 | 1.091 | 4.940 | OS | Univariate |
| Taghavi N 2010 | 3.946 | 0.430 | 30.860 | OS | Multivariable |
| Liu J 2012 | 2.139 | 1.199 | 3.816 | OS | Survival curve |
| Shiozaki A 2013 | 2.379 | 1.700 | 3.313 | OS | Multivariable |
| Zhang Y 2014 | 1.867 | 1.029 | 3.387 | OS | Multivariable |
| Lin Y 2016 | 2.623 | 1.005 | 8.147 | OS | Multivariable |
Note: HR = hazard ratio; LL = lower confidence interval limit; UL = upper confidence interval limit; OS = overall survival.