Table 1.
Baseline characteristics
Features | Overall n = 26 (%) | Primary (n = 13) | Secondary (n = 13) |
---|---|---|---|
Age | |||
Median | 59.5 y | 51 y | 62 y |
Range | 26‐78 y | 26‐78 y | 34‐77 y |
Sex | |||
Female | 16 (62) | 9 | 7 |
Male | 10 (38) | 4 | 6 |
ECOG | |||
0 | 16 (62) | 9 | 7 |
1 | 7 (27) | 3 | 4 |
2 | 1 (4) | 1 | 0 |
3 | 2 (8) | 0 | 2 |
Stage at original MZL diagnosis | |||
I | 12 (46) | 11 | 1 |
II | 2 (8) | 1 | 1 |
III | 0 | 0 | 0 |
IV | 12 (46) | 1 | 11 |
B symptoms | |||
Present | 2 (8) | 0 | 2 |
Absent | 23 (88) | 13 | 10 |
Missing | 1 (4) | 0 | 1 |
CNS location | |||
Dural only | 13 (50) | 9 | 4 |
Parenchymal only | 5 (19) | 3 | 2 |
Leptomeningeal only | 1 (4) | 0 | 1 |
Other | 3 (12) | 0 | 3 |
Missing | 4 (15) | 1 | 3 |
Serum LDH | |||
Normal | 16 (62) | 9 | 7 |
Elevated | 7 (27) | 3 | 4 |
Missing | 3 (12) | 1 | 2 |
Treatment | |||
RTx alone | 1 (4) | 0 | 1 |
CTx alone | 5 (19) | 0 | 5 |
SX + RTx | 7 (27) | 5 | 2 |
SX + CTx | 6 (23) | 4 | 2 |
RTx + CTx | 0 | 0 | 0 |
SX + RTx +CTx | 4 (15) | 3 | 1 |
Missing | 3 (12) | 1 | 2 |
PF event | |||
No | 13 (50) | 11 | 2 |
Yes | 10 (38) | 2 | 8 |
Missing | 3 (12) | 0 | 3 |
Outcome | |||
Alive | 22 (85) | 13 | 9 |
Dead | 4 (15) | 0 | 4 |
Data expressed as number (percentage).
Abbreviations: CTx, chemotherapy; LDH, lactate dehydrogenase; PF, progression free; RTx, radiotherapy; SX, surgery.