Table 1.
(a) Medical and demographic variables for the entire sample, by region (Western [Europe and North America] vs Eastern [Asia] sites), and subgroup (SHH, Group 4, Group 3 and WNT). (b) Missing medical and demographic variables for the entire sample, by region (Western [Europe and North America] vs Eastern [Asia] sites), and subgroup
| (a) Medical and demographic variable |
Entire sample n = 76 |
Western sample n = 51 |
Eastern sample n = 25 |
SHH n = 16 |
Group 4 n = 34 |
Group 3 n = 15 |
WNT n = 7 |
|---|---|---|---|---|---|---|---|
| Age at diagnosis (years) | |||||||
| Mean (SD) | 6.71 (3.56) | 6.82 (3.41) | 6.48 (3.9) | 4.65 (3.60) | 7.62 (3.18) | 6.52 (4.05) | 8.28 (2.45) |
| Range | 0.33‐17.0 | 0.33‐14.95 | 1.0‐17.0 | 0.33‐14.33 | 3.04‐14.95 | 2.0‐17.0 | 5.81‐12.0 |
| Time since diagnosis (years) | |||||||
| Mean (SD) | 6.58 (4.00) | 6.31 (4.14) | 7.13 (3.74) | 8.13 (4.05) | 6.41 (3.84) | 6.76 (4.85) | 4.87 (2.23) |
| Range | 0.54‐17.67 | 0.92‐17.67 | 0.54‐15.91 | 2.67‐15.91 | 0.54‐16.51 | 1.24‐17.67 | 0.92‐6.88 |
| Sex (% male) | 70.7 | 68.0 | 76.0 | 62.5 | 67.6 | 86.7 | 57.1 |
| Metastatic status (% M+) | 25.3 | 28.0 | 20.0 | 18.8 | 29.4 | 20.0 | 42.9 |
| Gross total resection (%) | 85.1 | 79.6 | 88.0 | 93.8 | 75.8 | 93.3 | 85.7 |
| CSI (%) | |||||||
| Standard dose | 31.5 | 40.8 | 12.5 | 25.0 | 30.3 | 35.7 | 42.9 |
| Reduced dose | 65.8 | 57.1 | 83.3 | 62.5 | 69.7 | 64.3 | 57.1 |
| None | 2.7 | 2.0 | 4.2 | 12.5 | 0.0 | 0.0 | 0.0 |
| Chemotherapy (%) | 98.7 | 98.0 | 100.0 | 93.8 | 100.0 | 100.0 | 100.0 |
| (b) Missing medical and demographic variable | Entire sample | Western sample | Eastern sample | SHH | Group 4 | Group 3 | WNT |
|---|---|---|---|---|---|---|---|
| Age at diagnosis | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Time since diagnosis | 2 | 2 | 0 | 0 | 1 | 0 | 0 |
| Sex | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Metastatic status | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Resection | 2 | 2 | 0 | 0 | 1 | 0 | 0 |
| CSI | 3 | 2 | 1 | 0 | 1 | 1 | 0 |
| Chemotherapy | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Subgroup | 4 | 4 | 0 | N/A | N/A | N/A | N/A |
Abbreviations: M+, metastatic; SD, standard deviation; SHH, sonic hedgehog; WNT, wingless.