Table 4.

Differences between HUI2 and HUI3 single‐attribute utility scores and multi‐attribute utility function scores (ie overall burden of morbidity) as a function of subgroup, demographic, and medical variables

	Subgroup			Gender			Metastatic status			CSI			Resection			Chemotherapy
	χ2	ε2	P‐value	χ2	ε2	P‐value	χ2	ε2	P‐value	χ2	ε2	P‐value	χ2	ε2	P‐value	χ2	ε2	P‐value
HUI2
Sensation	2.42	0.032	.49	0.37	0.005	.55	0	0.000	.96	0.822	0.011	.66	0.415	0.006	.52	1.56	0.021	.21
Mobility	4.56	0.061	.21	1.09	0.015	.30	0.02	0.000	.90	0.81	0.011	.67	0.014	0.000	.91	0.51	0.007	.48
Cognition	4.46	0.060	.22	0.26	0.003	.61	1.26	0.017	.26	3.149	0.042	.21	1.735	0.023	.19	1.61	0.021	.20
Self‐care	3.3	0.044	.35	0.000	0.000	.99	1.26	0.017	.26	1.64	0.022	.44	0.003	0.000	.95	0.230	0.003	.63
Emotion	1.27	0.017	.74	2.51	0.033	.11	1.18	0.016	.28	3.102	0.041	.21	1.363	0.018	.24	0.71	0.010	.40
Pain	5.42	0.072	.14	0.01	0.000	.95	3.98	0.053	.05*	1.190	0.016	.55	1.327	0.018	.25	0.39	0.005	.53
Overall	2.37	0.032	.50	0.01	0.000	.91	1.03	0.014	.31	1.194	0.016	.55	0.096	0.001	.76	2.17	0.029	.14
HUI3
Vision	1.37	0.018	.71	1.240	0.017	.27	0.66	0.009	.42	0.369	0.005	.83	5.230	0.070	.02*	0.7	0.009	.40
Hearing	4.730	0.063	.19	0.01	0.000	.92	4.59	0.061	.03*	2.138	0.029	.34	4.150	0.055	.04*	0.21	0.003	.65
Speech	0.55	0.007	.91	0	0.000	.95	0.11	0.001	.74	1.162	0.016	.56	0.627	0.008	.43	0.45	0.006	.50
Cognition	3.03	0.040	.39	0.26	0.003	.61	0.5	0.007	.48	3.046	0.041	.22	0.830	0.011	.36	1.36	0.018	.24
Ambulation	4.480	0.060	.21	0.73	0.010	.39	0.06	0.001	.80	0.594	0.008	.74	0.067	0.001	.80	0.48	0.006	.49
Dexterity	0.03	0.000	1.00	0.39	0.005	.53	0.09	0.001	.76	2.067	0.028	.36	0.220	0.003	.64	1.77	0.024	.18
Emotion	3.26	0.043	.35	1.81	0.024	.18	0	0.000	.96	3.446	0.046	.18	0.000	0.000	1.00	0.46	0.006	.50
Pain	2.47	0.033	.48	0.38	0.005	.54	4.81	0.064	.03*	0.890	0.012	.64	0.211	0.003	.65	0.36	0.005	.55
Overall	2.15	0.029	.54	0.06	0.001	.81	0.7	0.009	.40	0.775	0.010	.68	0.423	0.006	.52	0.92	0.012	.34

Single‐attribute utility scores have interval scale properties ranging from 1.00 (no morbidity) to 0.00 (worst level of impairment). For overall burden of morbidity (multi‐attribute utility function scores) a score of 1.00 indicates perfect health, a score of 0.89‐0.99 indicates mild burden of morbidity, a score of 0.70‐0.88 indicates moderate burden of morbidity and a score of <0.70 indicated severe burden of morbidity. Epsilon‐squared (ε²) effect sizes: small = 0.01 to <0.08, medium = 0.08 to <0.26, and large = ≥0.26.

Abbreviations: CSI, craniospinal irradiation; ε², epsilon‐squared; χ², chi‐square.

^*Indicates a statistically significant difference (P ≤ .05).