Table 3.
Factors associated to artificial nutrition use in the last 7 and 31 d before death: multivariate analysis (logistic regressions)
| The last 7 d before death | The last 31 d before death | |||
|---|---|---|---|---|
| N = 11 723 (2.9%) | P | N = 20 429 (5.1%) | P | |
| aOR (95% CI) | aOR (95% CI) | |||
| Sex | ||||
| Men (vs women) | 1.11 (1.06‐1.15) | <.001 | 1.07 (1.03‐1.10) | <.001 |
| Age at death (years) | ||||
| ≥80 (vs <80) | 0.48 (0.45‐0.50) | <.001 | 0.48 (0.46‐0.50) | <.001 |
| Year of death | ||||
| 2014 (vs 2013) | 0.99 (0.94‐1.04) | .646 | 1.01 (0.97‐1.05) | .820 |
| 2015 (vs 2013) | 0.91 (0.86‐0.96) | <.001 | 0.93 (0.89‐0.97) | <.001 |
| 2016 (vs 2013) | 0.98 (0.93‐1.03) | .410 | 0.95 (0.91‐0.99) | .013 |
| Hospitalization stay duration (days) | ||||
| [8‐31] (vs ≤7) | 1.54 (1.45‐1.64) | <.001 | 1.84 (1.76‐1.93) | <.001 |
| >31 (vs ≤7) | 1.44 (1.38‐1.49) | <.001 | 1.73 (1.67‐1.79) | <.001 |
| Hospital type | ||||
| Speciality (vs non speciality) | 1.53 (1.47‐1.59) | <.001 | 1.45 (1.41‐1.50) | <.001 |
| Cancer localization | ||||
| Digestivea (vs NDHANb) | 1.18 (1.14‐1.23) | <.001 | 1.31 (1.27‐1.35) | <.001 |
| Head and neck (vs NDHANb) | 2.24 (2.09‐2.40) | <.001 | 2.71 (2.57‐2.85) | <.001 |
| Metastasis | ||||
| Presence (vs no) | 0.76 (0.73‐0.79) | <.001 | 0.79 (0.77‐0.82) | <.001 |
| Comorbidities (Charlson)c | ||||
| 1 or 2 (vs absence) | 1.27 (1.21‐1.32) | <.001 | 1.12 (1.16‐1.24) | <.001 |
| 3 or 4 (vs absence) | 1.26 (1.19‐1.33) | <.001 | 1.19 (1.14‐1.24) | <.001 |
| ≥5 (vs absence) | 1.30 (1.21‐1.39) | <.001 | 1.24 (1.18‐1.31) | <.001 |
| Malnutrition | ||||
| Mild (vs absence) | 2.53 (2.23‐2.88) | <.001 | 2.47 (2.25‐2.71) | <.001 |
| Moderate (vs absence) | 1.58 (1.49‐1.68) | <.001 | 1.74 (1.67‐1.82) | <.001 |
| Severe (vs absence) | 1.77 (1.69‐1.85) | <.001 | 2.19 (2.12‐2.27) | <.001 |
| Other casesd (vs absence) | 1.82 (1.61‐2.05) | <.001 | 1.91 (1.75‐2.09) | <.001 |
| Specific biologic/clinical situationse | ||||
| Presence of at least 1f (vs no) | 1.40 (1.34‐1.46) | <.001 | 1.53 (1.47‐1.58) | <.001 |
| Dementia | ||||
| Presence (vs no) | 0.62 (0.54‐0.71) | <.001 | 0.62 (0.56‐0.68) | <.001 |
| Chemotherapy useg | ||||
| Yes (vs no) | 1.05 (0.98‐1.11) | .148 | 1.14 (1.10‐1.18) | <.001 |
| Palliative care useg | ||||
| Yes (vs no) | 0.39 (0.37‐0.40) | <.001 | 0.53 (0.51‐0.54) | <.001 |
Bold values: P‐values < .05.
Abbreviation: aOR (95% CI), adjusted odd ratio with the 95% confidence interval.
Digestive cancers: oesophageal, pancreas, and other digestive localizations.
NDHAN: Non‐digestive and non‐head‐and‐neck cancers.
Charlson modified score (excluding malignancies/metastasis).
Protein energy malnutrition non‐defined according to severity.
Biological and/or clinical situation(s) potentially source of prescription of artificial nutrition.
Cachexia and/or anorexia and/or metabolic disorders and/or mucositis/stomatitis and/or hepatic disorders and/or digestive symptoms and/or respiratory symptoms and/or skin ulceration.
The last 7 or 31 d depending on the endpoint (last 7 or 31 d before death, respectively).