Table 2.
Comparison of fold change of DEGs found by microarray (Ambele et al., 2016) and RNA-Seq analysis of hASCs induced to adipogenesis for 24 hours.
| Gene Symbol | Ambele et al., 2016 |
Total |
Poly |
||||
|---|---|---|---|---|---|---|---|
| Fold Change (linear) (Induced vs. Control) | ANOVA p-value (Induced vs. Control) | FDR p-value | log (FC) | FDR | log (FC) | FDR | |
| RGCC | 120,79 | 0,000,043 | 0,021,075 | 9,583,771 | 7,4E-144 | 10,01,033,521 | 2,5E-158 |
| PDK4 | 117,74 | 0,008,184 | 0,196,563 | 10,74,217 | 2,7E-137 | 8,81,757,307 | 1,7E-134 |
| EDNRB | 42,56 | 0,002,059 | 0,108,275 | 8,857,964 | 5,9E-116 | 10,32,436,544 | 2,5E-118 |
| CPM | 39,19 | 0,000,108 | 0,031,133 | 5,56,893 | 1,4E-77 | 4,91,979,404 | 4,9E-68 |
| HSD11B1 | 33,09 | 0,000,026 | 0,018,656 | 8,381,996 | 6,21E-87 | 8,694,888,945 | 1,8E-105 |
| MT1G | 23,03 | 0,000,077 | 0,026,736 | 3,835,517 | 0,002207 | 4,195,654,196 | 1,21E-07 |
| CRISPLD2 | 22,36 | 0,000,204 | 0,040,274 | 4,590,795 | 6,39E-35 | 4,859,236,086 | 7,1E-46 |
| ALOX15B | 21,68 | 0,000,002 | 0,00823 | 5,07437 | 0,000377 | 8,639,929,326 | 4,24E-12 |
| RGS2 | 20,16 | 0,000,006 | 0,011,074 | 4,606,101 | 1,32E-82 | 4,619,559,121 | 1,77E-72 |
| MT1M | 18,13 | 0,000,007 | 0,011,546 | 4,810,601 | 5,15E-34 | 4,637,185,323 | 4,81E-22 |
| NRCAM | 15,79 | 0,000,003 | 0,008,747 | 4,224,598 | 7,56E-61 | 4,143,294,976 | 5,24E-53 |
| GALNT15 | 14,38 | 0,001,332 | 0,088,615 | 3,370,781 | 2,05E-36 | 3,596,168,949 | 5,36E-32 |
| METTL7A | 14,17 | 0,000,335 | 0,048,518 | 4,043,354 | 3,56E-50 | 3,604,936,968 | 7,84E-40 |
| RASD1 | 11,05 | 0,000,784 | 0,069,374 | 5,547,823 | 8,68E-33 | 6,325,800,774 | 3,22E-67 |
| MAOA | 11,02 | 0,003,463 | 0,137,229 | 6,964,571 | 1,49E-86 | 7,582,062,683 | 3E-99 |
| SLC7A8 | 11,02 | 0,000,043 | 0,021,075 | 2,525,769 | 1,38E-10 | 3,414,536,268 | 1,74E-21 |
| TMEM158 | 10,99 | 0,001,909 | 0,105,973 | 4,135,615 | 3,05E-11 | 5,365,494,547 | 3,27E-59 |
| RASSF4 | 9,73 | 0,013,127 | 0,237,516 | 5,061,252 | 5,4E-36 | 4,96,042,219 | 8,79E-44 |
| CNR1 | 8,93 | 0,011,758 | 0,227,199 | 8,273,254 | 9,56E-27 | 8,865,825,896 | 1,23E-41 |
| IMPA2 | 8,79 | 0,000,438 | 0,052,725 | 3,204,121 | 1,19E-33 | 3,05,840,331 | 3,61E-36 |
| MT1X | 8,71 | 0,000,079 | 0,027,098 | 6,363,681 | 1,63E-22 | 5,437,885,251 | 6,15E-52 |
| IFI44L | 8,69 | 0,000,016 | 0,014,596 | 5,650,076 | 1,68E-47 | 4,336,312,458 | 6,67E-20 |
| AOX1 | 7,48 | 0,000,093 | 0,028,629 | 3,396,809 | 1,76E-43 | 2,846,878,561 | 1,03E-34 |
| CHRDL1 | 7,04 | 0,003,695 | 0,141,227 | 2,032,227 | 8,05E-06 | 1,924,777,838 | 1,21E-06 |
| CCDC69 | 7,03 | 0,006,861 | 0,182,149 | 2,166,616 | 3,16E-09 | 2,844,188,223 | 2,26E-10 |
| GREB1L | 6,89 | 0,002,413 | 0,118,843 | 2,167,808 | 2,02E-18 | 2,498,854,887 | 7,07E-19 |
| NEFL | 6,87 | 0,00952 | 0,209,266 | 6,608,846 | 1,67E-61 | 6,487,955,633 | 8,54E-39 |
| NEFM | 6,8 | 0,035,527 | 0,352,753 | 0,594,523 | 0,766,164 | 0,80,997,685 | 0,458,129 |
| LMO3 | 6,16 | 0,000,567 | 0,058,703 | 5,840,284 | 8,09E-93 | 6,675,000,848 | 8,8E-111 |
| MT1F | 6,06 | 0,037,603 | 0,360,309 | 4,109,284 | 0,003035 | 4,114,984,701 | 4,29E-05 |
| PER1 | 5,92 | 0,000,064 | 0,024,908 | 3,146,617 | 3,76E-26 | 3,538,664,108 | 7,09E-33 |
| SAMHD1 | 5,8 | 0,000,776 | 0,068,866 | 2,499,278 | 1,24E-19 | 2,709,463,657 | 1,23E-22 |
| PDE7B | 5,71 | 0,000,074 | 0,026,566 | 2,938,241 | 8,12E-17 | 3,654,733,538 | 8,85E-32 |
| CIDEC | 5,63 | 0,01131 | 0,224,821 | 7,62,812 | 4,08E-28 | 7,415,130,592 | 8,09E-38 |
| FOXO1 | 5,56 | 0,000,431 | 0,052,725 | 3,252,448 | 9,86E-27 | 3,481,251,159 | 1,68E-20 |
| IRS2 | 5,35 | 0,000,019 | 0,016,123 | 2,655,314 | 5,44E-11 | 2,658,758,457 | 2,66E-24 |
| SAT1 | 5,25 | 0,000,011 | 0,013,102 | 2,670,537 | 3,94E-11 | 3,093,685,397 | 3,17E-28 |
| RNF144A | 5,06 | 0,000,884 | 0,074,754 | 4,520,335 | 5,62E-15 | 4,770,149,744 | 1,13E-13 |
| REV3L | 5,05 | 0,00008 | 0,02719 | 2,55,853 | 3,27E-25 | 2,413,279,429 | 1,06E-28 |
| IL1R1 | 5,04 | 0,000,029 | 0,019,043 | 1,963,723 | 2,12E-18 | 2,170,891,211 | 3,75E-21 |
| SLC19A2 | 4,97 | 0,00066 | 0,063,288 | 2,722,488 | 4,2E-14 | 3,27,026,976 | 1,35E-39 |
| C10orf10 | 4,93 | 0,013,379 | 0,239,323 | 2,321,615 | 5,45E-17 | 2,371,303,595 | 5,8E-26 |
| NID1 | 4,87 | 0,003,368 | 0,135,243 | 2,025,193 | 7,76E-16 | 2,358,309,296 | 1,01E-18 |
| KLF15 | 4,76 | 0,004,771 | 0,157,798 | 4,807,511 | 5,3E-27 | 5,175,157,422 | 2,87E-36 |
| FKBP5 | 4,7 | 0,000,184 | 0,039,103 | 4,412,921 | 4,86E-48 | 4,385,642,188 | 2,8E-34 |
| GLUL | 4,66 | 0,000,013 | 0,014,085 | 2,441,417 | 8,79E-17 | 2,130,908,436 | 4,36E-15 |
| PRUNE2 | 4,59 | 0,001,501 | 0,093,669 | 2,863,764 | 3,18E-28 | 2,049,045,765 | 1,87E-11 |
| FASN | 4,56 | 0,000,154 | 0,036,445 | 2,238,049 | 1,18E-16 | 2,64,236,721 | 1,45E-23 |
| ANGPTL1 | 4,38 | 0,012,054 | 0,229,591 | 3,460,774 | 4,43E-27 | 3,112,552,243 | 8,43E-34 |
| WNT5A | 4,38 | 0,002703 | 0,124,034 | 1,844,243 | 1,22E-09 | 2,01,640,862 | 1,83E-15 |
| PIK3C2B | 4,37 | 0,006,708 | 0,18,066 | 4,55,401 | 4,42E-09 | 2,9,757,817 | 0,000872 |
| TSC22D3 | 4,32 | 0,000,151 | 0,036,125 | 3,638,564 | 5,31E-42 | 3,841,132,005 | 1,71E-44 |
| CDH20 | 4,21 | 0,000,393 | 0,050,838 | 8,486,391 | 3,51E-10 | 8,13,813,717 | 4,76E-10 |
| HIP1 | 4,21 | 0,000,053 | 0,022,892 | 1,533,995 | 2,02E-08 | 1,291,126,204 | 0,001741 |
| ZBTB16 | 4,18 | 0,000,087 | 0,027,826 | 9,040,063 | 1,34E-78 | 9,300,261,657 | 3,45E-76 |
| MME | 4,16 | 0,00024 | 0,041,932 | 2,142,862 | 1,47E-14 | 1,891,072,886 | 1,68E-10 |
| GAS1 | 4,11 | 0,000,407 | 0,051,911 | 3,337,304 | 1,12E-46 | 2,98,235,324 | 4,35E-42 |
| MT1E | 4,05 | 0,00125 | 0,086,384 | 3,954,136 | 6,94E-22 | 3,953,500,629 | 2,31E-68 |
| TMTC1 | 4,01 | 0,006,396 | 0,177,376 | 1,1612 | 1,81E-05 | 1,133,840,503 | 0,000267 |
| ADAMTSL1 | −4,03 | 0,000,168 | 0,038,063 | −1,37,591 | 7,8E-11 | −1,26,694,561 | 7,65E-07 |
| ITGA3 | −4,1 | 0,018,247 | 0,271,424 | −2,65,895 | 1,53E-14 | −2,51,334,663 | 6,3E-13 |
| E2F7 | −4,12 | 0,00039 | 0,050,838 | −2,84,783 | 1,28E-22 | −2,93,986,447 | 6,75E-22 |
| GINS2 | −4,15 | 0,021,165 | 0,288,914 | −2,36,118 | 2,05E-09 | −2,33,010,649 | 1,75E-13 |
| DUSP14 | −4,15 | 0,000,099 | 0,029,542 | −1,34,825 | 6,44E-07 | −1,62,871,791 | 4,99E-13 |
| ICAM1 | −4,2 | 0,002,545 | 0,121,542 | −0,42,473 | 0,730,455 | −0,48,762,359 | 0,544,911 |
| SMURF2 | −4,23 | 0,000,462 | 0,053,322 | −2,27,944 | 5,38E-26 | −2,24,431,984 | 6,32E-24 |
| FAM129A | −4,24 | 0,000,188 | 0,039,211 | −1,46,394 | 7,42E-12 | −1,20,811,435 | 0,00089 |
| FGL2 | −4,31 | 0,019,915 | 0,28,208 | 0,282,329 | 0,514,765 | 0,017,445,377 | 0,968,386 |
| HSPB7 | −4,44 | 0,010,967 | 0,221,978 | −1,9817 | 2,47E-18 | −1,98,497,474 | 2,17E-15 |
| FMN2 | −4,45 | 0,000,054 | 0,022,892 | −2,96,442 | 6,13E-28 | −3,5,027,012 | 1,78E-50 |
| FGF5 | −4,46 | 0,001,809 | 0,104,171 | −4,24,254 | 1,49E-18 | −3,60,650,567 | 3,61E-26 |
| SGOL1 | −4,59 | 0,006,871 | 0,182,149 | −3503 | 0,000169 | −2,5,583,294 | 2,97E-11 |
| ANKRD1 | −4,6 | 0,001,819 | 0,104,308 | −1,87,855 | 1,26E-14 | −1,91,012,655 | 1,09E-18 |
| NTN4 | −4,69 | 0,007,655 | 0,1903 | −1,59,132 | 1,39E-07 | −1,53,017,104 | 3,07E-08 |
| DRAM1 | −4,72 | 0,000,466 | 0,053,448 | −0,31,532 | 0,414,653 | −0,27,518,891 | 0,387,709 |
| SMAGP | −4,73 | 0,00536 | 0,164,354 | −2,99,995 | 1,35E-06 | −3,19,063,126 | 1,21E-12 |
| GDF15 | −4,75 | 0,0028 | 0,126,143 | −0,6388 | 0,273,194 | −0,55,899,591 | 0,15,433 |
| SEMA3D | −4,78 | 0,043,316 | 0,379,719 | −2,47,423 | 3,65E-10 | −2,8,541,466 | 1,29E-24 |
| TBC1D2 | −4,83 | 0,000,023 | 0,01717 | −3,31,394 | 2,36E-31 | −2,68,770,313 | 2,42E-21 |
| SKA1 | −4,89 | 0,001,783 | 0,103,744 | −2,2233 | 1,29E-15 | −2,56,280,893 | 2,67E-22 |
| GPR133 | −4,92 | 0,00305 | 0,130,327 | −2,10,295 | 4,18E-09 | −1,79,272,973 | 6,46E-08 |
| FGF2 | −5,01 | 0,000,336 | 0,048,518 | −3,23,847 | 1,06E-22 | −3,2,984,631 | 8,5E-33 |
| RAB3B | −5,06 | 0,00006 | 0,024,259 | −2,89,455 | 1,61E-33 | −2,71,126,656 | 1,06E-35 |
| DACT1 | −5,21 | 0,000,068 | 0,025,539 | −1,93,568 | 2,25E-09 | −1,78,266,976 | 1,46E-09 |
| SLC9A7 | −5,24 | 0,003,136 | 0,131,871 | −2,76,362 | 1,94E-16 | −2,12,515,742 | 6,67E-14 |
| GALNT12 | −5,24 | 0,005,206 | 0,162,365 | −2,87,133 | 8,25E-10 | −1,49,336,491 | 0,000391 |
| FST | −5,29 | 0,000,846 | 0,072,981 | −2,12,037 | 1,85E-13 | −2,12,003,115 | 1,02E-09 |
| NEK7 | −5,34 | 0,000,151 | 0,036,125 | −2,26,857 | 6,06E-19 | −2,72,554,749 | 5,29E-20 |
| IER3 | −5,36 | 0,000,014 | 0,014,085 | −2,48,028 | 2,14E-17 | −2,86,733,609 | 1,58E-26 |
| MYBL1 | −5,37 | 0,005,019 | 0,160,736 | −2,5528 | 1,86E-18 | −2,67,503,786 | 4,47E-26 |
| DOK5 | −5,48 | 0,000,028 | 0,019,043 | −2,13,303 | 2,38E-16 | −2,13,132,492 | 1,55E-17 |
| LPXN | −5,69 | 0,004,656 | 0,155,542 | −1,36,606 | 0,016,002 | −2,99,973,926 | 1,32E-14 |
| DIAPH3 | −5,79 | 0,000,148 | 0,035,982 | −3,13,824 | 1,51E-30 | −2,83,385,136 | 1,4E-22 |
| KCND2 | −5,94 | 0,005,904 | 0,171,879 | −3,27,698 | 2,53E-31 | −2,93,320,861 | 3,63E-22 |
| GREM2 | −6,01 | 0,000,744 | 0,067,469 | −2,41,739 | 5,53E-26 | −2,25,181,116 | 6,13E-23 |
| ARNTL2 | −6,12 | 0,002,989 | 0,128,943 | −2,32,456 | 1,76E-12 | −2,07,141,405 | 9,66E-12 |
| PTPRB | −6,2 | 0,000,175 | 0,038,908 | −4,97,634 | 3,37E-58 | −4,47,132,516 | 2,53E-42 |
| MMP1 | −6,25 | 0,00034 | 0,048,586 | −3,12,988 | 1,87E-10 | −3,47,944,063 | 6,86E-08 |
| ALPK2 | −6,33 | 0,000,224 | 0,041,323 | −2,47,245 | 2,1E-26 | −2,69,629 | 6,69E-37 |
| KLF2 | −6,49 | 0,000,046 | 0,021,075 | −3,27,652 | 8,57E-07 | −3,96,887,126 | 3,55E-20 |
| TM4SF1 | −6,61 | 0,019,561 | 0,279,336 | −1846 | 0,001055 | −1,52,614,968 | 0,044,901 |
| MYCT1 | −6,85 | 0,000,000,147 | 0,003227 | −8,08559 | 3,41E-07 | −6,6,405,274 | 2,97E-18 |
| NOV | −7,04 | 0,000,634 | 0,062,021 | −3,82,171 | 4,37E-18 | −3,73,758,601 | 1,82E-28 |
| OXTR | −7,22 | 0,001,265 | 0,086,384 | −5,53,372 | 8,61E-27 | −5,43,323,833 | 6,06E-34 |
| TEK | −7,37 | 0,000,000,136 | 0,003227 | −2,45,975 | 2,53E-21 | −2,16,703,129 | 1,62E-23 |
| SLC4A4 | −8 | 0,000,035 | 0,020,495 | −3,04828 | 9,41E-24 | −3,07,718,419 | 4,79E-18 |
| PDE1C | −8 | 0,00061 | 0,061,035 | −2,94,725 | 1,92E-35 | −3,25,952,741 | 7,71E-46 |
| KRT18P10 | −8,11 | 0,000,239 | 0,041,932 | −4,32,262 | 4,06E-18 | −3,77,414,763 | 2,25E-08 |
| SCN9A | −8,28 | 0,003,494 | 0,137,508 | −2,85,813 | 3,25E-14 | −3,18,676,756 | 4,21E-20 |
| RHOJ | −8,29 | 0,000,014 | 0,014,085 | −3,25,494 | 8,47E-12 | −2,98,252,297 | 1,58E-13 |
| NGF | −8,68 | 0,000,000,913 | 0,006291 | −2,70,064 | 1,24E-14 | −2,6,218,191 | 4,91E-23 |
| CPED1 | −8,9 | 0,000018 | 0,01575 | −2,45,922 | 2,92E-14 | −2,52,098,464 | 4,72E-18 |
| ESM1 | −9 | 0,00608 | 0,174,056 | −6,04337 | 2,62E-17 | −6,75,845,961 | 3,97E-41 |
| CAP2 | −9,05 | 0,000,023 | 0,01717 | −2,97,654 | 8,76E-12 | −3,47,311,237 | 9,98E-21 |
| CH25H | −11,61 | 0,000,006 | 0,011,074 | −0,7949 | 0,308,795 | −0,85,740,999 | 0,105,523 |
| IL6 | −13,75 | 0,000,187 | 0,039,211 | −2,16,551 | 1,26E-07 | −2,92,639,867 | 3,22E-15 |
| ATP8B1 | −14,17 | 0,000,007 | 0,011,546 | −3,06986 | 3,42E-27 | −2,87,413,254 | 5,17E-29 |
| TNFRSF11B | −15,1 | 0,000,004 | 0,010,118 | −4,23,333 | 5,34E-55 | −4,58,516,491 | 7,48E-74 |
| KRT34 | −15,65 | 0,000,333 | 0,048,472 | −7,0997 | 1,45E-43 | −6,83,306,019 | 2,38E-34 |
| B3GALT2 | −19,75 | 0,000,009 | 0,011,546 | −3,49,733 | 2,57E-12 | −4,30,658,287 | 1,12E-49 |