Table 1.
Formulations | CWS-L | CWS-FL | CWS-PL | CWS-FPL |
---|---|---|---|---|
Liposome composition (mol ratio) | ||||
SPC | 90 | 89.5 | 89.9 | 89.5 |
CH | 10 | 10 | 10 | 9.9 |
DP5KF | 0.5 | 0.5 | ||
DP2KM | 0.1 | 0.1 | ||
Pep1 | 0.05 | 0.05 | ||
Physical properties | ||||
Size (nm) | 183.5 ± 0.21 | 187.5 ± 0.14 | 189.2 ± 0.23 | 189.4 ± 0.23 |
PDI | 0.28 ± 0.08 | 0.21 ± 0.05 | 0.27 ± 0.05 | 0.24 ± 0.08 |
ZP (mV) | −8.31 ± 0.37 | −14.29 ± 0.37 | 12.16 ± 0.25 | −12.11 ± 0.22 |
EE (%) | 61.32 ± 0.37 | 59.89 ± 0.16 | 60.12 ± 0.33 | 62.17 ± 0.52 |
DL (μg/mg) | 219.86 ± 3.53 | 223.49 ± 2.34 | 224.80 ± 2.77 | 210.75 ± 3.12 |
Data represent the mean ± SD (n = 3).