. 2019 Sep 26;15(1):52–62. doi: 10.1021/acschembio.8b00849

Table 2. SAR Studies of “A-ring” Analogs of HC106^a.

The HC106 analogs with different R-groups were synthesized. The reporter strain CDC1551 (hspX’::GFP) was treated with doses of each analog from 200 μM to 0.328 μM. The EC₅₀ values of fluorescence inhibition were calculated for each analog to determine their potency.

Table 2. SAR Studies of “A-ring” Analogs of HC106a.

Table 2. SAR Studies of “A-ring” Analogs of HC106^a.