Skip to main content
. 2020 Jan 20;75:e1498. doi: 10.6061/clinics/2020/e1498

Table 2. Summary of similar studies in the literature, including the present study results, with aqueous and/or vitreous humor analysis in patients with uveitis.

Description Number of individuals Uveitis Classification PCR Positivity Investigated Pathogens
Rothova et al. (14) 152 patients
40 controls
Posterior Overall positivity:*
29% (44/152)
34% (15/44 PCR; AH)
T. gondii
HSV, VZV, CMV
Santos et al. (12) 27 patients Anterior
Intermediate
Posterior
Panuveitis
19.2% (5/26; AH)
30% (6/20; VH)
T. gondii
HSV, VZV, CMV
M. tuberculosis
Kongyai et al. (21) 80 patients Posterior
Panuveitis
30% (24/80)
35% (19/54; AH)
19% (5/26; VH)
T. gondii
HSV, VZV, CMV
Scheepers et al. (27) 159 patients Anterior
Intermediate
Posterior
Panuveitis
59% *
(94/159; AH and/or VH)
T. gondii
HSV, VZV, CMV
M. tuberculosis
Errera et al. (30) 42 patients
16 controls
Anterior Overall positivity:*
38% (16/42; AH)
35.7% (5/14 PCR; AH)
HSV, VZV, CMV
Santos et al. (31) 55 patients
12 controls
Posterior (toxoplasmic retinochoroiditis) 37.2% (16/43; AH) T. gondii
Chronopoulos et al. (32) 45 patients Anterior
Intermediate
Posterior
Panuveitis
48.9% (22/45; AH) T. gondii
HSV, VZV,CMV, EBV
Kumar et al. (33) 126 patients
100 controls
Anterior
Intermediate
Posterior
Panuveitis
32.4% (12/37; AH)
23.6% (21/89; VH)
T. gondii
HSV,VZV, CMV
Calvo et al. (34) 14 patients Posterior (Acute retinal necrosis) 78.5% (11/14; AH) HSV, VZV
Elyashiv et al. (35) 28 patients Posterior 57% (16/28; AH) T. gondii
HSV, VZV, CMV
Present study 28 patients Anterior
Posterior
Panuveitis
41.7% (5/12; AH)
31.2% (5/12; VH)
T. gondii
HSV, CMV, EBV

PCR = polymerase chain reaction; AH = aqueous humor; VH = vitreous humor; T. gondii = Toxoplasma gondii; HSV = herpes simplex virus; VZV = Varicela zoster virus; CMV = cytomegalovirus; EBV = Epstein-Barr virus; M. tuberculosis = Mycobacterium tuberculosis.

*

These studies included other methods beyond PCR analysis.