Table 2. Summary of similar studies in the literature, including the present study results, with aqueous and/or vitreous humor analysis in patients with uveitis.
Description | Number of individuals | Uveitis Classification | PCR Positivity | Investigated Pathogens |
---|---|---|---|---|
Rothova et al. (14) | 152 patients 40 controls |
Posterior | Overall positivity:* 29% (44/152) 34% (15/44 PCR; AH) |
T. gondii HSV, VZV, CMV |
Santos et al. (12) | 27 patients | Anterior Intermediate Posterior Panuveitis |
19.2% (5/26; AH) 30% (6/20; VH) |
T. gondii HSV, VZV, CMV M. tuberculosis |
Kongyai et al. (21) | 80 patients | Posterior Panuveitis |
30% (24/80) 35% (19/54; AH) 19% (5/26; VH) |
T. gondii HSV, VZV, CMV |
Scheepers et al. (27) | 159 patients | Anterior Intermediate Posterior Panuveitis |
59% * (94/159; AH and/or VH) |
T. gondii HSV, VZV, CMV M. tuberculosis |
Errera et al. (30) | 42 patients 16 controls |
Anterior | Overall positivity:* 38% (16/42; AH) 35.7% (5/14 PCR; AH) |
HSV, VZV, CMV |
Santos et al. (31) | 55 patients 12 controls |
Posterior (toxoplasmic retinochoroiditis) | 37.2% (16/43; AH) | T. gondii |
Chronopoulos et al. (32) | 45 patients | Anterior Intermediate Posterior Panuveitis |
48.9% (22/45; AH) |
T. gondii HSV, VZV,CMV, EBV |
Kumar et al. (33) | 126 patients 100 controls |
Anterior Intermediate Posterior Panuveitis |
32.4% (12/37; AH) 23.6% (21/89; VH) |
T. gondii HSV,VZV, CMV |
Calvo et al. (34) | 14 patients | Posterior (Acute retinal necrosis) | 78.5% (11/14; AH) | HSV, VZV |
Elyashiv et al. (35) | 28 patients | Posterior | 57% (16/28; AH) |
T. gondii HSV, VZV, CMV |
Present study | 28 patients | Anterior Posterior Panuveitis |
41.7% (5/12; AH) 31.2% (5/12; VH) |
T. gondii HSV, CMV, EBV |
PCR = polymerase chain reaction; AH = aqueous humor; VH = vitreous humor; T. gondii = Toxoplasma gondii; HSV = herpes simplex virus; VZV = Varicela zoster virus; CMV = cytomegalovirus; EBV = Epstein-Barr virus; M. tuberculosis = Mycobacterium tuberculosis.
These studies included other methods beyond PCR analysis.