Appendix 1—figure 6. Effect of sodium blockers on ToR-ORd and ORd in fibre.

Membrane potential in fibre at four simulated conditions (control, half block of fast sodium, half block of late sodium, and half block of both fast and late sodium currents) in ToR-ORd (A) and ORd (B). In (C, D) is given the corresponding calcium transient. The measurements were taken in the node at the half of the fibre; consequently, action potentials in the conditions including I_Na block are delayed to the other traces, given corresponding conduction delay.