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. 2020 Jan 16;13:35–43. doi: 10.2147/JIR.S233381

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© 2020 Wolde et al.

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Effect of S. mansoni soluble egg antigen (SEA) and soluble worm compounds (SWA) on gene expression, cytokine production, and motility of monocytes of healthy volunteers. (A) SOCS-1, IL-10, and IL-12 expression as determined by Q-PCR. Fold induction (FI) of mRNA levels was determined using GAPDH as a reference gene. (B) TNF-α, IL-10, and IL-6 cytokine production was determined in culture supernatants using a multiplex bead immunoassay. (C) Average motility of monocytes was determined by live-cell imaging. All data are derived from six separate experiments using cells derived from different donors. *Significance is p<0.05.