Table 2. Odds ratios for coronary artery disease risk according to lipoprotein-associated apoC-III levels.
| Variable | Q1 | Q2 | Q3 | Q4 | Q5 |
|---|---|---|---|---|---|
| apoCIII-apoAI | |||||
| Model 1: adjusted for age, sex | 1.00 | 1.20 (0.92–1.57) | 1.27 (0.98–1.66) | 1.27 (0.97–1.65) | 1.42 (1.09–1.84) |
| Model 2: model 1 + BMI, smoking, diabetes, hypertensive and lipid-lowering drug use. | 1.00 | 1.19 (0.90–1.58) | 1.22 (0.92–1.62) | 1.11 (0.83–1.47) | 1.14 (0.86–1.52) |
| Model 3: model 2 + LDL-C, TG, and HDL-C | 1.00 | 1.12 (0.84–1.50) | 1.02 (0.75–1.37) | 0.88 (0.64–1.20) | 0.88 (0.64–1.21) |
| apoCIII-apoB | |||||
| Model 1: adjusted for age, sex | 1.00 | 0.98 (0.75–1.28) | 1.25 (0.96–1.62) | 1.32 (1.01–1.71) | 1.46 (1.12–1.89) |
| Model 2: model 1 + BMI, smoking, diabetes, hypertensive and lipid-lowering drug use. | 1.00 | 1.02 (0.76–1.36) | 1.16 (0.87–1.54) | 1.17 (0.88–1.55) | 1.28 (0.96–1.70) |
| Model 3: model 2 + LDL-C, TG, and HDL-C | 1.00 | 0.90 (0.67–1.22) | 0.97 (0.71–1.31) | 0.94 (0.68–1.29) | 0.96 (0.68–1.35) |
| apoCIII-Lp(a) | |||||
| Model 1: adjusted for age, sex | 1.00 | 0.97 (0.75–1.27) | 1.04 (0.80–1.36) | 1.26 (0.97–1.63) | 1.66 (1.29–2.15) |
| Model 2: model 1 + BMI, smoking, diabetes, hypertensive and lipid-lowering drug use. | 1.00 | 1.01 (0.76–1.35) | 0.93 (0.70–1.24) | 1.15 (0.87–1.52) | 1.35 (1.02–1.78) |
| Model 3: model 2 + LDL-C, TG, and HDL-C | 1.00 | 0.94 (0.70–1.26) | 0.82 (0.61–1.12) | 1.02 (0.75–1.38) | 0.99 (0.71–1.39) |
| Total apoCIII-apoB | |||||
| Model 1: adjusted for age, sex | 1.00 | 1.30 (0.98–1.73) | 1.04 (0.78–1.39) | 1.19 (0.89–1.59) | 1.22 (0.92–1.63) |
| Model 2: model 1 + BMI smoking, diabetes, hypertensive and lipid-lowering drug use. | 1.00 | 1.31 (0.96–1.78) | 0.99 (0.72–1.36) | 1.08 (0.79–1.47) | 1.03 (0.76–1.42) |
| Model 3: model 2 + LDL-C, TG, and HDL-C | 1.00 | 1.19 (0.86–1.63) | 0.84 (0.60–1.17) | 0.91 (0.64–1.28) | 0.86 (0.60–1.22) |
| Total apoCIII-apoAI | |||||
| Model 1: adjusted for age, sex | 1.00 | 1.30 (0.98–1.73) | 1.04 (0.78–1.39) | 1.19 (0.89–1.59) | 1.22 (0.92–1.63) |
| Model 2: model 1 + BMI smoking, diabetes, hypertensive and lipid-lowering drug use. | 1.00 | 1.31 (0.96–1.78) | 0.99 (0.72–1.36) | 1.08 (0.79–1.47) | 1.03 (0.76–1.42) |
| Model 3: model 2 + LDL-C, TG, and HDL-C | 1.00 | 1.19 (0.86–1.63) | 0.84 (0.60–1.17) | 0.91 (0.64–1.28) | 0.86 (0.60–1.22) |
| apoC-III | |||||
| Model 1: adjusted for age, sex | 1.00 | 1.18 (0.89–1.55) | 1.12 (0.86–1.47) | 1.42 (1.09–1.85) | 1.93 (1.49–2.51) |
| Model 2: model 1 + BMI, smoking, diabetes, hypertensive and lipid-lowering drug use. | 1.00 | 1.19 (0.89–1.58) | 1.02 (0.77–1.36) | 1.20 (0.90–1.59) | 1.50 (1.13–1.98) |
| Model 3: model 2 + LDL-C, TG, and HDL-C | 1.00 | 1.07 (0.80–1.43) | 0.91 (0.68–1.23) | 1.03 (0.76–1.39) | 1.20 (0.87–1.64) |
apoC-III, apolipoprotein C-III; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TG, triglyceride; apoCIII-apoAI, apoC-III content on apolipoprotein A-I containing lipoproteins; apoCIII-apoB, apoC-III content on apolipoprotein B-100 containing lipoproteins; apoCIII-Lp(a), apoC-III content on apolipoprotein(a).
Data represent odds ratios ± 95% CI, in different models with different adjustments.