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. 2019 Nov 26;295(3):690–700. doi: 10.1074/jbc.RA119.011349

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© 2020 Liu et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 1. — Generation and characterization of the R26-TLR mouse line. A, schematic showing the knock-in strategy of R26-TLR by homologous recombination. B and C, schematics showing the results after Dre-rox or Cre-loxP recombination. D, whole-mount bright-field and epifluorescence images of E13.5 embryos of R26-TLR, CAG-Dre;R26-TLR, CAG-Dre;ACTB-Cre;R26-TLR, and E15.5 embryos of ACTB-Cre;R26-TLR. E, immunostaining for ZsGreen and tdTomato on the indicated embryos sections in D. Yellow scale bars = 1 mm; white scale bars = 100 μm. Each image is representative of five individual samples.