Table 2.

Modulation of VM by microRNAs (miRNAs).

miRNAs	Targets	Biological function	Cancer type	References
mir-200C, mir-183, mir-96, mir-182 mir-299-5P mir-125a, Let-7e mir-193b miR-204	ZEB-1 OPN IL-6, IL-6R,STAT3 DDAH1 PI3K, c-SRC, FAK	Inhibit VM, increased proliferation, chemotherapy, poor prognosis	Breast	(82) (83) (84) (85) (86)
mir-124	AmotL1, STAT3	Inhibit migration, invasion, EMT, VM	Cervical, oral	(87, 102)
mir-200a mir-27b miR-765	EphA2 VE-cadherin VEGFA, AKT1, SRC-α	Poor survival, inhibit VM, Inhibit migration, invasion	Ovarian	(88) (89) (90)
miR-9 mir-26b miR-Let-7f mir-584-3p miR-141	STMN1 EphA2 POSTN ROCK1 EphA2	Decreased tumor growth, VM, glioma grades II, III and IV, prognostic indicator, proliferation, migration, invasion	Glioma	(91) (92) (93) (94) (95)
miR-27a miR-17 miR-27a-3p mir-101 mir-29b	CDH5, SMAD2, TGFBR1, VEGF VEGF, HIF1A, MMP2 VE-cadherin TGF-BR1,Smad2 SDF1 IL-6, STAT3, MMP-2	Poor prognosis, represses early metastasis, EMT, VM	Hepatocellular	(96) (97) (98) (99)
miR-186	TWIST1	Inhibit tumor progression, invasion, colony formation, EMT	Prostate	(100)
miR-490-3p	TR4, Vimentin	Promote metastasis, VM	ccRCC	(81)
miR-409-3p	ANG	Suppresses proliferation, tumor growth, metastasis, VM	Fibrosarcoma	(101)