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. 2020 Jan 14;7:437. doi: 10.3389/fbioe.2019.00437

Figure 1.

Figure 1

(A) Schematic diagram representing intervertebral disc in (B). Note the nucleus pulposus (NP) at the center of the disc; the concentric rings (lamellae) of the AF are arranged in alternating fibers that are angled ~±30° from each other [(A) Adapted from Kandel et al. (2014)]. (B) Photograph taken of the superior view of dissected porcine lumbar intervertebral discs (aged 6-month) (Scale bar = 1 cm). (C–E) Scanning Electron Microscopy images demonstrating the superior view of the annular fibrosus lamellar layers. Images highlight the angle-ply fiber network between adjacent layers. (C–E) are magnified regions of interest observed within (A), which are represented by the white dashed square (Scale bars: C = 500 μm at x65 magnification; D = 100 μm at x500 magnification; E = 10 μm at x2,700 magnification).