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. 2020 Jan 14;7:359. doi: 10.3389/fcell.2019.00359

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Copyright © 2020 Kang, Sun, Tang, Zhou and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Dynamic DEGs regulated by F. nucleatum in a time-dependent manner. (A) Venn analysis of time-course DEGs and genes with significantly enriched profiles in F. nucleatum-stimulated GMSCs. (B) Heatmap of the 5 dynamic DEGs generated by time-series F. nucleatum infection. The relative gene expression of the dynamic DEGs: (C) PLCG2, (D) CHI3L2, (E) SH2D2A, (F) NLRP3, as determined by qRT-PCR. ^∗P < 0.05, ^∗∗P < 0.01 and ^∗∗∗P < 0.001.