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. 2020 Jan 14;9:447. doi: 10.3389/fcimb.2019.00447

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Copyright © 2020 Cesur, Siraj, Uddin, Durmuş and Çakır.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Significantly enriched pathways (FDR < 10⁻⁴) regarding the targets from (A) sputum-macrophage (SM) and (B) human body fluid (HBF) simulations. The pathways that appear specifically in SM medium (A) point to the common functions of SM-specific conditionally essential genes. Only a subset of the pathways in (A) covers all pathways identified for the HBF medium (B). For each pathway, the bar shows number of putative targets involved in that pathway. The pathways from KEGG pathway database is given by gray bars while the bars representing BioCyc pathways are highlighted in claret red.