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. 2020 Jan 20;11:388. doi: 10.1038/s41467-019-14205-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Klebsiella pneumonia GRM2 locus. Structural shell BMC-H proteins cmcA, cmcB, cmcC, and cmcE are colored in green, and BMC-P protein cmcD is colored in yellow. Core enzymes CutF (aldehyde dehydrogenase), CutO (alcohol dehydrogenase), CutC (choline lyase), CutD (glycyl-radical activating enzyme), and CutH (phosphotransacylase) are colored in blue. Regulatory and transporter genes are colored in gray. The genes have been named according to previous research¹⁵. b C-terminal amino acid sequences of three cmcC variants—cmcC (native), cmcC′ (mutated), and cmcC_trunc (truncated).