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. 2020 Jan 20;11(1):41. doi: 10.1038/s41419-020-2232-7

Fig. 7. Proposed mechanism of FOXD2-AS1-mediated STAT3 activation in LSCC.

Fig. 7

Upregulated FOXD2-AS1 promoted transcriptional activity of STAT3, by serving as scaffold of STAT3 and PRMT5, and subsequently conferred the cancer stemness and chemoresistance in LSCC.