TABLE 1.

DSM 5 PTSD symptom cluster and some rodent behavior correlates.

DSM 5 PTSD symptom cluster	Rodent behavior correlate	Relevant citations
Intrusions (Cluster B)	Spontaneous recovery of freezing during fear extinction	Rescorla, 2004 (Review) Nalloor et al., 2011 (Rat) VanElzakker et al., 2014 (Review)
Avoidance (Cluster C)	Avoidance of trauma related cues	Vazdarjanova and McGaugh, 1998 (Rat) Philbert et al., 2011 (Mouse) Chen et al., 2012 (Rat) Villain et al., 2018 (Mouse)
Altered cognition and mood (Cluster D)	Impaired fear extinction and anxiety-like behavior (D4), impaired performance on spatial water maze, depressive-like, and anhedonia-like behavior (D5, 7)	D4 Walf and Frye, 2007 (Review) Nalloor et al., 2011 (Rat) Paredes and Morilak, 2019 (Review) D5, 7 Cohen et al., 2003 (Rat) Hales et al., 2014 (review)
Altered arousal and reactivity (Cluster E)	Increased risk assessment and avoidance of open spaces (E3), elevated acoustic startle response (E4), impaired attention in set shifting (E5), disturbed sleep (E6)	E3 Goswami et al., 2012 (Rat) E4 Koch and Schnitzler, 1997 (Review) Rasmussen et al., 2008 (Rat) Nalloor et al., 2011 (Rat) Matar et al., 2013 (Rat) E5 George et al., 2015 (Rat) Heisler et al., 2015 (Mouse) E6 Philbert et al., 2011 (Mouse)

These are sample studies that are not meant to be completely inclusive.