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. 2020 Jan 20;10:701. doi: 10.1038/s41598-020-57534-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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YAP1 knockdown suppressed cell proliferation, invasion and tumour growth in NF2-mutant sRCC. (A) Cell proliferation of YAP1 knockdown in JHRCC12 cells. Data are presented as mean ± SD. **P < 0.005. (B) Cell number and morphology change after YAP1 knockdown. (C) Invasion assay for scramble-control (sh-scr) and YAP1 knockdown (sh-YAP) in JHRCC12 cells. Data presented are mean ± SD. ***P < 0.001. (D) Tumour growth curve of scramble-control (sh-scr) and YAP1 knockdown (sh-YAP) JHRCC12 cells.