Table 2.

Correlation between the MRI analysis of UBOs and neuropsychological findings: main characteristics of the neuroimaging studies included.

References	Participants	Mean age (SD); range	Neuroimaging acquisition	Neuroimaging results	Neuropsychological correlations
Moore et al. (29)	84 NF1	12,04; r: 8-16	MRI T2	Thalamic T2H location	IQ, memory, motor, distractibility and attention
Feldman et al. (30)	67 NF1 20 controls	16,3 (8,7); r: 6-3716,6 (8,6); r: 6-39	MRI T2	Decreased T2H (basal ganglia, thalamus) on 3-year follow up	Improved IQ (+8 points)
Payne et al. (31)	18 NF1 5 controls	12,4 (2,5); r: 8-16,812,0 (2,3); r: 8,9-15,2	MRI T2	Decreased T2H on 18-year follow up	Improved IQ
Piscitelli et al. (32)	49 NF1	10,2 (2,9); r: 6-16,9	MRI T2	Cerebellar T2H location	Lower scores for subtest information and vocabulary on the WISC-III, arithmetic and vocabulary, total IQ, fluid reasoning IQ
Roy et al. (33)	36 NF1	9,62 (1,74); r: 7-12,92	MRI T2	Number, size, location T2H	No correlation with executive functions and IQ

IQ, intellectual quotient; MRI, magnetic resonance imaging; NF1, neurofibromatosis type 1; r, range; SD, standard deviation; T2H, T2 hyperintensity; UBOs, unidentified bright objects; WISC-III, Wechsler Intelligence Scale for Children III.