Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 14;10:3032. doi: 10.3389/fmicb.2019.03032

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Martínez-Zavala, Barboza-Pérez, Hernández-Guzmán, Bideshi and Barboza-Corona.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Comparison of the modular structure of chitinases of B. thuringiensis with different bacterial chitinases and the three-dimensional structure of the ChiA74 from B. thuringiensis. (I) Modular alignment between different bacterial chitinases. Protein sequences were analyzed using the Interpro webserver (www.ebi.ac.uk/interpro/beta/) and the figure was built with the program DOG 1.0 (Ren et al., 2009). The nomenclature used in the CAZy database was maintained. Signal peptide, sp; catalytic domains, GH18; CID, chitinase insertion domain; carbohydrate-binding module, CBM; fibronectin type III domain, FnIII. Chitinase (Chi) of: Bt, B. thuringiensis (accession number AF424979.1); Bl, B. licheniformis (QAS14701.1); Sp, Serratia proteamaculans (AGF70636.1); Sm, S. marcescens (ABI79318.1); Sm, S. marcescens AHH32576.1; Bc, B. cereus (FRI-35 AFQ09088.1); Cm, Chitinolyticbacter meiyuanensis (ATN39892.1); Ah, Aeromonas hydrophila (AAG09437.1); Tk, Thermococcus kodakarensis (BAA88380). (II) Crystal structure of the chitinase ChiA74 of B. thuringiensis with little additions in the nomenclature to match with (I). The catalytic region (CD) corresponds to the GH18, and chitin binding domain (CBD) to the CBM2 showed in panel (I). This clarification is also shown in (II). The three-dimensional structure was first reported by our group in Juárez-Hernández et al. (2019), Scientific Reports, available online at https://doi.org/10.1038/s41598-019-39464-z.