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. 2020 Jan 14;10:1573. doi: 10.3389/fphys.2019.01573

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Copyright © 2020 Greenwood and Stott.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gβγ enhances Kv7.4 currents in CHO expression system. Top panels show representative traces of currents generated in cells expressing Kv7.4 either with the control intracellular solution (left) or with 250 ng/ml Gβγ purified from bovine brain (right). Zero current is indicated by the dashed line. Mean IV relationship of Kv7.4 currents in control (n = 7) or with 250 ng/ml Gβγ (n = 4) is shown in bottom panel. Data was analyzed by Bonferroni post hoc test following a two-way ANOVA. p < 0.01 is denoted (^∗∗) and p < 0.005 is denoted (^∗∗∗).