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. 2020 Jan 14;10:1573. doi: 10.3389/fphys.2019.01573

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Copyright © 2020 Greenwood and Stott.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gβ1 knockdown effects on renal artery myocytes. (A) Mean data of whole cell K⁺ currents recorded in rat renal artery myocytes in Gβ1 morpholino in control (n = 10, N = 4) or in the presence of 10 μm/L linopirdine (n = 8, N = 4). Mean fluorescence intensity of (B) Gβ1 (n = 20–22, N = 4) (C) Gβ3 (n = 15, N = 3) or (D) Kv7.4 (n = 14, N = 3) in renal artery myocytes in control morpholino or Gβ1 morpholino. “n” = number of cells and “N” = number of animals. Electrophysiology data was analyzed by Bonferroni post hoc test following a two-way ANOVA. IF data was analyzed by one-way ANOVA with Bonferroni post hoc analysis. p < 0.01 is denoted (^∗∗) and p < 0.005 is denoted (^∗∗∗).