Table 2.

Comparison of genes with different mutation frequency in both groups.

Gene	Cytoband	(A) AYA	(B) OA	p-value	Gene	Cytoband	(A) AYA	(B) OA	p-value
ASXL1	20q11.21	3 (11.11%)	2 (1.19%)	0.0197	EP300	22q13.2	1 (3.70%)	1 (0.60%)	0.258
KMT2C	7q36.1	5 (18.52%)	8 (4.76%)	0.0206	ERBB4	2q34	1 (3.70%)	1 (0.60%)	0.258
ERBB3	12q13.2	3 (11.11%)	4 (2.38%)	0.0569	FLT4	5q35.3	1 (3.70%)	1 (0.60%)	0.258
FAT1	4q35.2	2 (7.41%)	2 (1.19%)	0.093	FOXA1	14q21.1	1 (3.70%)	1 (0.60%)	0.258
SOX9	17q24.3	2 (7.41%)	2 (1.19%)	0.093	KIAA1217	10p12.2-p12.1	1 (3.70%)	1 (0.60%)	0.258
KRAS	12p12.1	1 (3.70%)	22 (13.10%)	0.136	MALT1	18q21.32	1 (3.70%)	1 (0.60%)	0.258
AR	Xq12	1 (3.70%)	0 (0.00%)	0.138	MEN1	11q13.1	1 (3.70%)	1 (0.60%)	0.258
AXIN2	17q24.1	1 (3.70%)	0 (0.00%)	0.138	MST1R	3p21.31	1 (3.70%)	1 (0.60%)	0.258
CDKN1A	6p21.2	1 (3.70%)	0 (0.00%)	0.138	NCOA3	20q13.12	1 (3.70%)	1 (0.60%)	0.258
DICER1	14q32.13	1 (3.70%)	0 (0.00%)	0.138	TCF3	19p13.3	1 (3.70%)	1 (0.60%)	0.258
FGFR4	5q35.2	1 (3.70%)	0 (0.00%)	0.138	TSC2	16p13.3	1 (3.70%)	1 (0.60%)	0.258
GATA2	3q21.3	1 (3.70%)	0 (0.00%)	0.138	ZFHX3	16q22.2-q22.3	1 (3.70%)	1 (0.60%)	0.258
GNA11	19p13.3	1 (3.70%)	0 (0.00%)	0.138	PIK3CA	3q26.32	3 (11.11%)	10 (5.95%)	0.261
GRIN2A	16p13.2	1 (3.70%)	0 (0.00%)	0.138	BAP1	3p21.1	2 (7.41%)	24 (14.29%)	0.262
HIST3H3	1q42.13	1 (3.70%)	0 (0.00%)	0.138	TERT	5p15.33	0 (0.00%)	8 (4.76%)	0.296
JAK1	1p31.3	1 (3.70%)	0 (0.00%)	0.138	TP53	17p13.1	8 (29.63%)	39 (23.21%)	0.307
LAMC1	1q25.3	1 (3.70%)	0 (0.00%)	0.138	SMAD4	18q21.2	1 (3.70%)	15 (8.93%)	0.317
MDM2	12q15	1 (3.70%)	0 (0.00%)	0.138	ATM	11q22.3	1 (3.70%)	14 (8.33%)	0.354
NOL4	18q12.1	1 (3.70%)	0 (0.00%)	0.138	KMT2D	12q13.12	2 (7.41%)	7 (4.17%)	0.361
PDCD1	2q37.3	1 (3.70%)	0 (0.00%)	0.138	APC	5q22.2	1 (3.70%)	2 (1.19%)	0.362
PHOX2B	4p13	1 (3.70%)	0 (0.00%)	0.138	ATR	3q23	1 (3.70%)	2 (1.19%)	0.362
PLK2	5q11.2	1 (3.70%)	0 (0.00%)	0.138	BRD4	19p13.12	1 (3.70%)	2 (1.19%)	0.362
RABGAP1L	1q25.1	1 (3.70%)	0 (0.00%)	0.138	GATA1	Xp11.23	1 (3.70%)	2 (1.19%)	0.362
RASAL2	1q25.2	1 (3.70%)	0 (0.00%)	0.138	IGF1R	15q26.3	1 (3.70%)	2 (1.19%)	0.362
SOX17	8q11.23	1 (3.70%)	0 (0.00%)	0.138	KDM5A	12p13.33	1 (3.70%)	2 (1.19%)	0.362
STAG2	Xq25	1 (3.70%)	0 (0.00%)	0.138	PTCH1	9q22.32	1 (3.70%)	2 (1.19%)	0.362
TACC2	10q26.13	1 (3.70%)	0 (0.00%)	0.138	XPO1	2p15	1 (3.70%)	2 (1.19%)	0.362
TGFBR2	3p24.1	1 (3.70%)	0 (0.00%)	0.138	DOT1L	19p13.3	0 (0.00%)	6 (3.57%)	0.404
ARID1B	6q25.3	2 (7.41%)	3 (1.79%)	0.142	CDH1	16q22.1	1 (3.70%)	3 (1.79%)	0.452
CTNNB1	3p22.1	2 (7.41%)	3 (1.79%)	0.142	EPHA5	4q13.1-q13.2	1 (3.70%)	3 (1.79%)	0.452
KMT2A	11q23.3	2 (7.41%)	3 (1.79%)	0.142	IDH2	15q26.1	1 (3.70%)	3 (1.79%)	0.452
FGFR2	10q26.13	5 (18.52%)	16 (9.52%)	0.144	MAP2K1	15q22.31	1 (3.70%)	3 (1.79%)	0.452
PBRM1	3p21.1	5 (18.52%)	16 (9.52%)	0.144	MAP3K1	5q11.2	1 (3.70%)	3 (1.79%)	0.452
SMARCA4	19p13.2	2 (7.41%)	4 (2.38%)	0.195	POLE	12q24.33	1 (3.70%)	3 (1.79%)	0.452
NRAS	1p13.2	2 (7.41%)	5 (2.98%)	0.25	SETD2	3p21.31	1 (3.70%)	3 (1.79%)	0.452
ASXL2	2p23.3	1 (3.70%)	1 (0.60%)	0.258	ARID2	12q12	0 (0.00%)	5 (2.98%)	0.471
CARD11	7p22.2	1 (3.70%)	1 (0.60%)	0.258	ARID1A	1p36.11	5 (18.52%)	35 (20.83%)	0.507
CREBBP	16p13.3	1 (3.70%)	1 (0.60%)	0.258	IDH1	2q34	7 (25.93%)	41 (24.40%)	0.516
EIF4A2	3q27.3	1 (3.70%)	1 (0.60%)	0.258