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. 2020 Jan 14;13:1362. doi: 10.3389/fnins.2019.01362

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Copyright © 2020 Yan, Wang, Miao, Kwapong, Lu, Ma, Chen, Tu and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Group differences in functional connectivity (FC) between individuals with neuromyelitis optica spectrum disorder (NMOSD) and controls. The blue dots represent the seed points, and the red dots represent the remaining brain regions displaying differences in FC. The lines represent the functional connections between the seed points and the different brain regions. (A) shows the right lingual gyrus; (B) shows the left thalamus; (C) shows the left calcarine gyrus. The FC values in right lingual gyrus (A), left thalamus (B) and left calcarine gyrus (C) were significantly reduced (P < 0.05) in NMOSD patients when compared to HC.