Table 1.
Ensemble Gene ID | Gene Symbol | Log2Fold Change | P-value | adj. P-value | Main finding | Study type |
---|---|---|---|---|---|---|
ENSG00000019991 | HGF | 3.81 | 9.27E-07 | 0.004 | Reported upregulation in schizophrenia by CMC40 | Expression |
ENSG00000167371 | PRRT2 | 1.38 | 3.75E-05 | 0.031 | CNVs at this gene genomic position have been associated with schizophrenia48,49 | Genetic |
ENSG00000120738 | EGR1 | 1.36 | 6.24E-05 | 0.045 | First reported to be associated with schizophrenia by PGC8 Reported upregulation in schizophrenia51 | Genetic Expression |
ENSG00000171608 | PIK3CD | −0.79 | 6.23E-05 | 0.045 | Evidence for link between the NRG1-ErbB4 signaling pathway and PIK3CD in schizophrenia70 | Expression |
ENSG00000185742 | C11orf87 | 1.00 | 6.77E-05 | 0.046 | First reported to be associated with schizophrenia by PGC8 | Genetic |
ENSG00000164342 | TLR3 | 2.34 | 0.00022 | 0.09 | Reported de novo missense mutations associated with schizophrenia62 | Genetic |
ENSG00000152527 | PLEKHH2 | 1.79 | 0.00026 | 0.097 | Reported de novo missense mutations in schizophrenia patients67 | Genetic |
ENSG00000179388 | EGR3 | 2.72 | 0.00025 | 0.097 | Reported SNPs associated with schizophrenia56–59 | Genetic |
CMC: CommonMind Consortium; PGC: Psychiatric Genomics Consortium.