Table 1.
Clinico-pathological characteristics of the 1770 patients.
| RTb (+) (n = 1317) | RT (−) (n = 453) | p* | ||
|---|---|---|---|---|
| Age at diagnosisa | <50 | 701 (53.2%) | 177 (39.1%) | <0.001 |
| ≥50 | 616 (46.8%) | 276 (60.9%) | ||
| ER | Negative | 420 (32.3%) | 170 (37.9%) | 0.032 |
| Positive | 882 (67.7%) | 278 (62.1%) | ||
| PR | Negative | 575 (44.2%) | 245 (54.7%) | <0.001 |
| Positive | 726 (55.8%) | 203 (45.3%) | ||
| HER2 | Negative | 966 (76.3%) | 279 (64.6%) | <0.001 |
| Positive | 300 (23.7%) | 153 (35.4%) | ||
| p-S6K1 | Negative | 319 (24.2%) | 128 (28.3%) | 0.091 |
| Positive | 998 (75.8%) | 325 (71.7%) | ||
| Mass size | <2 cm | 779 (59.1%) | 258 (57.0%) | 0.439 |
| ≥2 cm | 538 (40.9%) | 195 (43.0%) | ||
| Node status | Negative | 792 (60.5%) | 243 (54.0%) | 0.017 |
| Positive | 518 (39.5%) | 207 (46.0%) | ||
| Histology | IDC | 1134 (86.1%) | 395 (87.2%) | 0.830 |
| ILC | 59 (4.5%) | 19 (4.2%) | ||
| Others | 124 (9.4%) | 39 (8.6%) | ||
| Histologic grade | G1,2 | 777 (65.8%) | 264 (65.2%) | 0.427 |
| G3 | 403 (34.2%) | 141(34.8%) | ||
| Surgery | Breast conserving | 1044(79.3%) | 26(5.7%) | <0.001 |
| Total mastectomy | 273(20.7%) | 427(94.3%) | ||
| Loco-regional recurrence | Negative | 1279 (97.1%) | 432 (95.4%) | 0.094 |
| Positive | 38 (2.9%) | 21 (4.6%) | ||
| Biologic subtype | Luminal A | 746 (59.5%) | 206 (48.6%) | <0.001 |
| Luminal B | 168 (13.4%) | 73 (17.1%) | ||
| HER2 | 130 (10.4%) | 79 (18.5%) | ||
| Triple negative | 209 (16.7%) | 69 (16.2%) |
aFrequency (%).
bRadiotherapy.
*Pearson’s chi-square test and Fisher’s exact test.