Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 20;10:643. doi: 10.1038/s41598-019-57218-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

RNA expressions of the genes associated with therapeutic response and improved outcome to anti-PD-1. (a) The RNA expression of the gene CD137 is significantly higher in DCB group compared to NDB group (t-test, P = 2.78e⁻³) (b). The Kaplan-Meier plots of the patients with high and low RNA expression of each gene indicated that the PFS is higher in the patients with high expressions of CD137, but not statistically significant (log-rank, P = 0.082) (c). The OS does not show statistically significant difference for CD137 (log-rank P = 0.179). (d) The RNA expression of the PSBM9 gene is significantly higher in DCB group compared to NDB group (t-test, P = 6.66e⁻³).(e). PFS is significantly higher in patients with high PSMB9 RNA expression (log-rank, P = 4.13e⁻³) (f). OS is similar between two groups (log-rank P = 0.53).