Table 1.

Key fibrinolysis factors measured by ELISA in platelet‐free plasma and euglobulin fraction

	n	Plasma concentration		Correlation with ECLT		EuFr concentration		Correlation with ECLT		Reduction in EuFr (%)
		Mean ± SD	Sp r	95% CI	P value	Mean ± SD	Sp r	95% CI	P value	Mean ± SEM
aPAI‐1	31	214.4 ± 381.4 nM	0.74	0.52 to 0.87	<0.001	7.7 ± 16.4 nM	0.38	0.02 t6o 0.67	<0.05	96.9 ± 1.3
t‐PA	36	4.1 ± 5.2 PM	−0.03	−0.39 to 0.61	0.88	1.1 ± 1.7 PM	−0.40	−0.88 to (−0.27)	<0.01	52.4 ± 9.3
α2AP	16	0.7 ± 1.4 µM	0.11	−0.42 to 0.59	0.68	0.02 ± 0.005 µM	0.56	0.07‐0.83	<0.05	95.4 ± 0.8
α2MG	36	2.2 ± 1.7 µM	−0.15	−0.46 to 0.2	0.40	0.007 ± 0.008 µM	0.15	−0.19 to 0.47	0.37	99.1 ± 0.5
Plasminogen	35	1.7 ± 0.5 µM	0.38	0.05 to 0.64	<0.05	1.5 ± 0.6 µM	−0.09	0.42 to 0.26	0.61	20.4 ± 2.9

Correlation between ECLT and plasma/EuFr protein levels, and protein reduction in euglobulin fraction compared to initial plasma is shown.

α₂AP, α₂‐antiplasmin; α₂MG, α₂‐macroglobulin; aPAI‐1, active plasminogen activator inhibitor‐1; CI, confidence interval; EuFr, euglobulin fractionation; ECLT, euglobulin clot lysis time; Sp r, Spearman's correlation coefficient; SD, standard deviation; SEM, standard error of the mean; t‐PA, tissue‐type plasminogen activator.