Table 1.
Cell | Overall platelet dimensions | α ‐Granule properties | Dense granule properties | Canalicular system propertiesa | Mitochondria properties | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelet volume (μm3) | Short axis length (μm) | Long axis length (μm) | α‐Granule number | Average α‐granule short axis (μm) | Average α‐granule long axis (μm) | Mean α‐granule volume (μm³) | α‐Granule volume fraction | Dense granule number | Mean dense granule volume (μm³) | Dense granule volume fraction | Open CS volume (μm³) | Closed CS volume (μm³) | Total CS volume (μm³) | CS volume fraction | Mitochondrial number | Mitochondrial volume fraction | |
Donor 1, M, 21 y | |||||||||||||||||
Platelet 1 | 14.80 | 2.09 | 4.71 | 42 | 0.225 | 0.286 | 0.017 | 0.047 | 6 | 0.009 | 0.004 | 1.14 | 0.58 | 1.71 | 0.115 | 18 | 0.016 |
Platelet 2 | 8.70 | 1.43 | 4.06 | 58 | 0.282 | 0.361 | 0.019 | 0.126 | 5 | 0.011 | 0.006 | 0.34 | 0.78 | 1.12 | 0.128 | 15 | 0.027 |
Platelet 3 | 3.90 | 1.01 | 3.02 | 30 | 0.296 | 0.338 | 0.017 | 0.129 | 4 | 0.009 | 0.009 | 0.02 | 0.09 | 0.11 | 0.027 | 3 | 0.023 |
Platelet 4 | 7.40 | 2.06 | 3.65 | 19 | 0.322 | 0.382 | 0.035 | 0.093 | 5 | 0.010 | 0.007 | 0.04 | 0.64 | 0.68 | 0.092 | 3 | 0.011 |
Platelet 5 | 7.10 | 1.20 | 4.02 | 50 | 0.273 | 0.339 | 0.018 | 0.128 | 3 | 0.009 | 0.004 | 0.44 | 0.23 | 0.67 | 0.094 | 16 | 0.031 |
Platelet 6 | 6.00 | 1.50 | 3.57 | 41 | 0.206 | 0.255 | 0.009 | 0.063 | 2 | 0.010 | 0.002 | 0.03 | 0.44 | 0.47 | 0.078 | 17 | 0.027 |
Platelet 7 | 7.40 | 1.21 | 3.75 | 47 | 0.251 | 0.309 | 0.013 | 0.084 | 4 | 0.006 | 0.003 | 0.05 | 0.49 | 0.53 | 0.072 | 12 | 0.020 |
Platelet 8 | 3.90 | 1.21 | 2.89 | 23 | 0.226 | 0.273 | 0.011 | 0.063 | 3 | 0.005 | 0.004 | 0.03 | 0.37 | 0.40 | 0.103 | 12 | 0.028 |
Platelet 9 | 5.30 | 1.28 | 3.40 | 40 | 0.246 | 0.285 | 0.011 | 0.081 | 4 | 0.005 | 0.004 | 0.34 | 0.11 | 0.45 | 0.086 | 8 | 0.018 |
Platelet 10 | 8.10 | 1.92 | 3.50 | 45 | 0.262 | 0.327 | 0.021 | 0.114 | 8 | 0.014 | 0.014 | 0.03 | 0.59 | 0.79 | 0.097 | 6 | 0.013 |
Donor 1 Mean | 7.30 | 1.49 | 3.66 | 40 | 0.259 | 0.316 | 0.017 | 0.093 | 4.4 | 0.009 | 0.006 | 0.26 | 0.43 | 0.69 | 0.089 | 11.0 | 0.021 |
Standard error of the mean | 1.00 | 0.12 | 0.17 | 4 | 0.011 | 0.013 | 0.002 | 0.010 | 0.5 | 0.001 | 0.001 | 0.11 | 0.07 | 0.14 | 0.009 | 1.8 | 0.002 |
Donor 2, F, 37 y | |||||||||||||||||
Platelet 1 | 9.60 | 1.57 | 4.89 | 89 | 0.277 | 0.321 | 0.013 | 0.118 | 6 | 0.013 | 0.008 | 0.03 | 0.29 | 0.32 | 0.034 | 15 | 0.020 |
Platelet 2 | 7.00 | 1.49 | 4.26 | 33 | 0.305 | 0.358 | 0.017 | 0.081 | 4 | 0.009 | 0.005 | 0.04 | 0.29 | 0.33 | 0.046 | 12 | 0.018 |
Platelet 3 | 9.80 | 1.64 | 5.13 | 30 | 0.289 | 0.337 | 0.027 | 0.056 | 6 | 0.009 | 0.006 | 0.09 | 0.14 | 0.22 | 0.023 | 14 | 0.015 |
Platelet 4 | 8.10 | 1.47 | 4.79 | 45 | 0.307 | 0.368 | 0.021 | 0.117 | 9 | 0.013 | 0.015 | 0.02 | 0.26 | 0.28 | 0.035 | 13 | 0.018 |
Platelet 5 | 5.30 | 1.24 | 4.03 | 24 | 0.294 | 0.349 | 0.014 | 0.065 | 8 | 0.005 | 0.008 | 0.11 | 0.21 | 0.32 | 0.060 | 13 | 0.017 |
Platelet 6 | 4.30 | 1.00 | 3.45 | 32 | 0.229 | 0.282 | 0.012 | 0.088 | 4 | 0.012 | 0.011 | 0.14 | 0.29 | 0.43 | 0.099 | 14 | 0.028 |
Platelet 7 | 13.10 | 1.98 | 4.73 | 141 | 0.259 | 0.312 | 0.013 | 0.141 | 6 | 0.013 | 0.006 | 0.62 | 0.92 | 3.56 | 0.118 | 13 | 0.013 |
Platelet 8 | 7.80 | 1.55 | 3.87 | 37 | 0.232 | 0.280 | 0.011 | 0.051 | 3 | 0.006 | 0.002 | 0.12 | 0.96 | 1.08 | 0.138 | 8 | 0.011 |
Platelet 9 | 5.70 | 2.42 | 3.10 | 52 | 0.249 | 0.297 | 0.011 | 0.099 | 8 | 0.016 | 0.023 | 0.67 | 0.74 | 1.41 | 0.248 | 7 | 0.019 |
Platelet 10 | 9.20 | 1.72 | 3.83 | 77 | 0.228 | 0.266 | 0.008 | 0.065 | 8 | 0.008 | 0.007 | 1.11 | 0.38 | 1.50 | 0.163 | 6 | 0.008 |
Donor 2 Mean | 8.00 | 1.61 | 4.21 | 56 | 0.267 | 0.317 | 0.015 | 0.088 | 6.2 | 0.011 | 0.009 | 0.29 | 0.45 | 0.74 | 0.097 | 11.5 | 0.017 |
Standard error of the mean | 0.80 | 0.12 | 0.21 | 12 | 0.010 | 0.011 | 0.002 | 0.010 | 0.6 | 0.001 | 0.002 | 0.12 | 0.10 | 0.18 | 0.023 | 1.0 | 0.002 |
Donor 3, M, 70 y | |||||||||||||||||
Platelet 1 | 6.10 | 1.26 | 4.15 | 22 | 0.202 | 0.237 | 0.006 | 0.020 | 5 | 0.004 | 0.003 | 0.08 | 0.39 | 0.46 | 0.076 | 3 | 0.009 |
Platelet 2 | 4.10 | 0.87 | 3.09 | 9 | 0.284 | 0.317 | 0.023 | 0.049 | 3 | 0.007 | 0.005 | 0.05 | 0.16 | 0.21 | 0.050 | 6 | 0.017 |
Platelet 3 | 6.10 | 1.28 | 2.98 | 45 | 0.247 | 0.285 | 0.014 | 0.102 | 7 | 0.007 | 0.008 | 0.11 | 0.46 | 0.56 | 0.092 | 11 | 0.028 |
Platelet 4 | 4.90 | 1.69 | 2.30 | 23 | 0.190 | 0.211 | 0.005 | 0.022 | 4 | 0.003 | 0.003 | 0.47 | 0.41 | 0.88 | 0.178 | 3 | 0.010 |
Platelet 5 | 8.90 | 1.29 | 3.61 | 44 | 0.249 | 0.280 | 0.011 | 0.057 | 4 | 0.006 | 0.003 | 0.98 | 0.28 | 1.26 | 0.142 | 10 | 0.019 |
Platelet 6 | 9.20 | 1.63 | 3.92 | 91 | 0.215 | 0.247 | 0.008 | 0.077 | 9 | 0.008 | 0.008 | 1.89 | 0.48 | 2.37 | 0.255 | 7 | 0.011 |
Platelet 7 | 10.20 | 1.32 | 4.54 | 56 | 0.254 | 0.298 | 0.013 | 0.071 | 6 | 0.021 | 0.013 | 1.60 | 0.28 | 1.88 | 0.184 | 10 | 0.012 |
Platelet 8 | 9.40 | 1.22 | 3.76 | 64 | 0.243 | 0.284 | 0.015 | 0.104 | 3 | 0.008 | 0.002 | 0.08 | 1.08 | 1.16 | 0.123 | 8 | 0.013 |
Platelet 9 | 8.40 | 1.27 | 3.57 | 116 | 0.239 | 0.267 | 0.009 | 0.127 | 14 | 0.010 | 0.016 | 1.37 | 0.32 | 1.69 | 0.200 | 17 | 0.030 |
Platelet 10 | 10.30 | 1.24 | 4.22 | 63 | 0.234 | 0.264 | 0.010 | 0.062 | 4 | 0.004 | 0.002 | 1.44 | 0.73 | 2.17 | 0.211 | 18 | 0.028 |
Donor 3 Mean | 7.80 | 1.31 | 3.61 | 53 | 0.236 | 0.269 | 0.011 | 0.069 | 5.9 | 0.008 | 0.006 | 0.81 | 0.46 | 1.26 | 0.151 | 9.30 | 0.018 |
Standard error of the mean | 0.70 | 0.07 | 0.21 | 10 | 0.009 | 0.010 | 0.002 | 0.011 | 1.1 | 0.002 | 0.002 | 0.23 | 0.09 | 0.23 | 0.021 | 1.60 | 0.003 |
All donor mean | 7.70 | 1.47 | 3.83 | 50.0 | 254 | 301 | 0.014 | 0.083 | 5.5 | 0.009 | 0.007 | 0.46 | 0.44 | 0.90 | 0.113 | 10.6 | 0.019 |
Standard error of the mean | 0.50 | 0.06 | 0.12 | 5.0 | 6 | 8 | 0.001 | 0.006 | 0.5 | 0.001 | 0.001 | 0.09 | 0.05 | 0.12 | 0.011 | 0.9 | 0.001 |