Table 2. Echocardiographic variables assessing the left atrial and left ventricular function.
| Variables | Pretreatment | Posttreatment | p-value |
|---|---|---|---|
| TDI lat A' | 10.7 ± 2.42 | 11.5 ± 2.59 | 0.18 |
| TDI sep A' | 10.2 ± 3.66 | 11.1 ± 3.7 | 0.2 |
| TDI A'ann | 9.48 ± 3.56 | 10.3 ± 3.38 | 0.12 |
| MR vel | 5.88 ± 0.402 | 6.08 ± 0.559 | 0.097 |
| LA/Ao ratio | 1.73 ± 0.33 | 1.67 ± 0.28 | 0.327 |
| LADmin | 3.07 ± 0.804 | 3 ± 0.791 | 0.46 |
| LADmid | 3.58 ± 0.834 | 3.58 ± 0.853 | 0.94 |
| LADmax | 4.04 ± 0.775 | 4.02 ± 0.875 | 0.74 |
| LAVmin | 14.5 ± 8.96 | 14.8 ± 10.7 | 0.72 |
| LAVmid | 22.7 ± 11.6 | 21.5 ± 12.6 | 0.33 |
| LAVmax | 31.6 ± 14.6 | 30.8 ± 16.6 | 0.6 |
| PasEmpD-FS | 0.118 ± 0.0745 | 0.112 ± 0.0592 | 0.7 |
| PasEmpV-EF | 0.291 ± 0.129 | 0.312 ± 0.0979 | 0.48 |
| ActEmpD-FS | 0.148 ± 0.0733 | 0.162 ± 0.0763 | 0.41 |
| ActEmpV-EF | 0.377 ± 0.163 | 0.343 ± 0.11 | 0.18 |
| CompEmpD-FS | 0.249 ± 0.0908 | 0.256 ± 0.0784 | 0.66 |
| CompEmpV-EF | 0.564 ± 0.128 | 0.549 ± 0.0974 | 0.52 |
| LV-FS | 41.7 ± 8.93 | 45.6 ± 10.6 | 0.013* |
| LV-EF | 67.8 ± 10.1 | 71 ± 10.5 | 0.032* |
| LV-ESVI | 27.8 ± 12.5 | 23.8 ± 11.8 | 0.003* |
(TDI lat A’): peak velocity of diastolic mitral annular motion determined by pulsed-wave tissue Doppler imaging at the level of the left ventricular free wall; (TDI sept A’): peak velocity of diastolic mitral annular motion determined by pulsed-wave tissue Doppler imaging at the level of the interventricular wall; (TDI A’ann): average of TDI lat A’ and TDI sep A’; (MR vel): mitral regurgitation velocity; (LA/Ao ratio): left atrium-to-aortic ratio; (LADmin): left atrial linear dimension at ventricular end-diastole; (LADmid): left atrial linear dimension immediately before the P wave on the ECG; (LADmax): left atrial linear dimension at the ventricular end-systole; (LAVmin): left atrial volume at ventricular end-diastole; (LAVmid): left atrial volume immediately before the P wave on the ECG; (LAVmax): left atrial volume at the ventricular end-systole; (PassEmpD-FS): LA passive function based on diameters; (ActEmpD-FS): LA active function based on diameters; (ComEmpD-FS): LA complete function based on diameters; (PassEmpV-EF): LA passive function based on volumes; (ActEmpV-EF): LA active function based on volumes; (ComEmpV-EF): LA complete function based on volumes; (LV): left ventricle; (FS): fractional shortening; (EF): ejection fraction; (ESVI): end-systolic volume index. Comparison of values at the initial diagnosis and at the time of the second echocardiography (1–6 months after starting pimobendan). Values are expressed as mean and standard deviation.
: Statistically significant p values.