Sample selection. Flow diagram shows the steps followed to recruit patients and controls, the number of patients included, and excluded, the reasons for the exclusions and the final sample. ECHO: echocardiogram; CG: control group; HFG: heart failure group; SEMPR: endocrine division, Department of Internal Medicine, Federal University of Paraná, Curitiba, PR, Brazil; HFG: heart failure group; LVEF: left ventricular ejection fraction (%).